background and aims. oral lichen planus (olp) is an immunologic disorder. a large number of studies have reported that lipid rafts have a key role in receptor signaling of lymphocytes. here, we explore the potential of lipid rafts as targets for the development of a new class of agents to down-modulate immune responses and treat autoimmune diseases. materials and methods. the present cross-sect...

OBJECTIVES To determine whether erosive osteoarthritis shares the same pattern of joint involvement and risk profile as increasing grades of non-erosive hand osteoarthritis. METHODS Participants were from two population-based cohorts, aged ≥50 years, reporting hand symptoms in the previous month. Interphalangeal joints were assessed for erosive osteoarthritis (Verbruggen-Veys erosive or remod...

background and aims. oral lichen planus is a relatively common chronic oral mucosal disease of unknown etiology. regarding numerous studies on the immunologic factors involved in the etiology of lichen planus, the present study evaluated the serum interleukin-17 (il-17) level in patients with erosive and non-erosive oral lichen planus. materials and methods. this descriptive analytical study in...

background and aims. the clinical management of oral lichen planus poses considerable difficulties to the clinician. in recent years, researchers have focused on the presence of pathogenic microorganisms such as candida albicans in the patients with refractory lichen planus. the aim of the present study was to investigate the prevalence of candida species in the erosive oral lichen planus lesio...

BACKGROUND The main aim of this cross-sectional study was to investigate the prevalence and severity of erosive tooth wear and its association with dental caries and socio-demographic factors among middle-aged Finnish adults. METHODS Of the total Northern Finland Birth Cohort 1966 (n = 12,058), a convenience sample (n = 3181 adults) was invited for an oral health examination of which 1962 (61...

Introduction: Oral Lichen Planus (OLP) is one of the most common mucocutaneous lesion, and its etiologic factors have not been elucidated yet. OLP has two different clinical forms including reticular and erosive. Mast cells function in non-specific immunology is an etiologic factor involved in the formation of lichen planus. This study aimed at determining the pattern of mast cells presence in ...

OBJECTIVES To investigate systemic inflammation and autoimmune response to citrullinated peptides in patients with erosive and non erosive 'lone' hand osteoarthritis (HOA) with no hip/knee involvement and their relationship with radiographic structural damage. METHODS Sera were obtained from a total of 99 patients with HOA (52 patients with erosive HOA and 47 patients with non-erosive HOA) an...

background: proliferating cell nuclear antigen (pcna) is a nuclear protein synthesized in the late g1 and s-phase of the cell cycle. detection of this protein represents a useful marker of the proliferation status of lesions. this study has been carried out to evaluate the cell proliferation rate in oral lichen planus (olp) and comparison between plaque and erosive lichen planus, which indicate...

A small number of systemic lupus erythematosus (SLE) patients develop an erosive disease. Some studies have suggested an association between anti-cyclic citrullinated (anti-CCP) antibodies and this pattern of arthritis, but their exact significance in SLE patients remains unclear. The aim of this study was to evaluate the prevalence of anti-CCP antibodies in SLE patients with different subsets ...