We report the detection of a strain of Seoul hantavirus (SEOV) in pet rats in England and Wales. The discovery followed an investigation of a case of haemorrhagic fever with renal syndrome in Wales. Hantavirus RNA was detected via real-time reverse transcription-pol-ymerase chain reaction (RT-PCR) and classic RT-PCR in pet rats belonging to the patient. Sequencing and phylogenetic analysis conf...

Dengue fever is an acute viral disease that can affect all age groups in tropical and subtropical countries. The predominant vectors are the mosquitoes namely Aedes aegypti and A.albopictus. Although there have been no case reports in Turkey due to DF, there is seroepidemiological evidence indicating the presence of Dengue virus (DENV) in Turkey. In this case report we presented an imported den...

BACKGROUND AND OBJECTIVES Autoantibodies are immunglobulins occurred directly against autoantigens that are known as endogen antigens. Autoimmune disease is an occasion that the body begins a fight against its own cells and tissues. The antibodies that are created by the body against its own cell nuclei are called as anti-nuclear antibodies (ANA), and one of the methods used for detection and p...

BACKGROUND/AIMS There is increasing interest in noninvasive tests for the assessment of Helicobacter pylori infection, and urine-based tests have been widely used as noninvasive tests to detect Helicobacter pylori infection. The aim of this study was to evaluate the adaptation and usefulness of urine antibody enzyme-linked immunosorbent assay and urine card tests in the clinical setting to dete...

BACKGROUND & OBJECTIVES Antinuclear antibodies (ANA) are serological hallmark of systemic lupus erythematosus (SLE). Conventionally, the test is carried out on human epithelial cells (HEp2) by indirect immunofluorescence (IIF) technique. Since culturing and maintaining HEp2 cells in the laboratory are labour intensive, in-house assays have given way to kits manufactured by commercial companies....

Dear Sir,COVID-19 is of paramount concern in the rheumatology community. As per current consensus, patients rheumatological diseases (RDs) are at higher risk SARS-CoV-2 infection than general population (high agreement but very low grade evidence); however, contradictory reports available regarding its seroprevalence and association with severity mortality. However, these inferences mainly base...

Background: PCR (Polymerase Chain Reaction) is generally considered the gold standard for confirming diagnosis in early stages of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. However, our rheumatology outpatient clinic we observed a significant discrepancy between clinical evidence COVID-19 and results. Objectives: Aim this retrospective study was to analyze significa...

Background Abberations of B cells have been implicated in the pathogenesis systemic sclerosis(SSc) [1] and CD21 low cells, which express high levels activation markers, recently associated with vascular manifestations SSc [2]. CD32 (FcγRII), comprised three isoforms A, C, is involved cell regulation antibody production. do not FcγRIIA mainly inhibitory FcγRIIB isoform [3]. Objectives The aim ou...

Abstract Background Preimplantation genetic analysis aims selecting the best embryo to transfer increasing chance of a successful pregnancy. However, failure in implantation euploid embryos is frequent practice assisted human reproduction, observed approximately 30 50% transfers, with no cause found most cases. Previous or active infectious may be associated infertility, but this topic still la...

Background: Coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) and its associated disease COVID-19 (Corona Virus Disease 2019) has become a worldwide pandemic since first cases in December 2019 Wuhan Province China. Until now little is known about the incidence course of routine setting rheumatology outpatient care. Objectives: Aim study was to identify with COVID-19, anal...