ABSTRACT We describe an integrated microchip for droplet analysis with electrospray ionization mass spectrometry (ESI-MS). The chip integrated multiple modules of droplet generator, droplet extraction interface, and monolithic ESI-emitter. A novel droplet extraction interface based on a hydrophilic tongue structure was developed to transfer droplet from segmented phase to aqueous phase with hig...

Background: Several multiphase flow analyses have been developed to predict the fate of particles used in inhalation drug delivery; however, the collapse of droplets during their passage through respiratory tract has not been investigated. Objective: To assess the probability of droplet collapse in the upper respiratory tract.Methods: A 3D model of mouth-to-second generation airway after the tr...

We investigate the dynamics of a droplet on a planar substrate as the droplet volume changes dynamically due to liquid being pumped in or out through a pore. We adopt a diffuse-interface formulation which is appropriately modified to account for a localized inflow-outflow boundary condition (the pore) at the bottom of the droplet, hence allowing to dynamically control its volume, as the droplet...

proper estimation of droplet growth rate plays a crucial role on appropriate prediction of supersonic separators performance for separation of fine droplets from a gas stream. up to now, all available researches employ empirical or semi-empirical correlations to define the relationship between droplet growth rate (dr/dt) and other operating variables such as temperatures (t and tl), pressure (p...

This work aims to study the characteristics of multi-nozzle spray cooling using CFD method based on the fundamentals of air flow and liquid droplet collision dynamics. A mathematical model for the two-phase flow was presented. The simulations were performed using a EulerianeLagrangian approach. Focus was placed on revealing the flow behavior with multiple nozzles, the droplet trajectory, and th...

In this paper, the turbulent air droplet flow inside a single passage of a curved type vane separator has been studied numerically. The simulation is based on the Eulerian - Lagrangian method. For turbulent air flow calculations, a computer code was developed to solve the Reynolds Averaged Navier Stokes (RANS) equations together with the equations of Reynolds Stress Transport Model (RSTM) o...

The objective of this research is to develop an accurate numerical method to be used in showing the deformation of a liquid fuel droplet in a convective field. To simultaneously solve the internal liquid droplet flow field as well as the external gas phase flow field, a nonstaggered rectangular grid system without any coordinate transformation is used. Transition from the gas field to the liqui...

Background. Transmission efficacy of Influenza in aerosols is dependent on environmental factors such as temperature, relative humidity (RH), airflow, andUV-light.We studied the impact of these factors on the recovery of an aerosolized wild-type Influenza virus. Methods. Influenza Avirus (A/WS/33 H1N1) was aerosolized via nebulizer (droplet nuclei) and airbrush (droplet nuclei/droplet mix). Vir...