from “must have” to “don’t need,” it is generally tossed on the scrapheap of consumer history. Just ask the people who invented the floppy disk. According to some health experts, the foreskin is the floppy disk of the male anatomy, a once-important flap of skin that no longer serves much purpose. But the foreskin also has many fans, who claim it still serves important protective, sensory and se...

In the early 1990s, researchers began looking at potassium channel openers for seizure control. Over the past 10 years, in vitro research and animal studies demonstrated that potassium channel openers could control seizure activity in a dose-dependent way.1-4 Clinical trials are now confirming these findings.5 Among the calcium channel openers that have been studied, the agent retigabine has co...

Trastuzumab, a monoclonal antibody directed at the HER2 receptor, is one of the most impressive targeted drugs developed in the last two decades. Indeed, when given in conjunction with chemotherapy, it improves the survival of women with HER2 positive breast cancer, both in advanced and in early disease. Its optimal duration, however, is poorly defined in both settings with a significant econom...

Aluminum anodes have been widely used in the cathodic protection of marine structures. However there are conditions in which these anodes become passivated or face some localized or unwanted corrosion, which influences their efficiency. Addition of alloying elements such as Zn and In not only have improved the efficiency of the anodes but also the effect of casting parameters such as ultra ...

people with alzheimer disease (ad) have decreases in brain cell function that may increase their risks as drivers. the changes in brain cells affect memory (at first, short-term memory and then much later, long-term memory) and other thinking functions. in addition, people with early ad, though often very functional in many areas of life, may not be as competent behind the wheel of a car as tho...