Autoregulatory feedback loops occur in the regulation of molecules ranging from ATP to MAP kinases to zinc. Negative feedback loops can increase a system's robustness, while positive feedback loops can mediate transitions between cell states. Recent genome-wide experimental and computational studies predict hundreds of novel feedback loops. However, not all physical interactions are regulatory,...

BACKGROUND Naïve-indirect comparisons are comparisons between competing clinical interventions' evidence from separate (uncontrolled) trials. Direct comparisons are comparisons within randomised control trials (RCTs). The objective of this empirical study is to test the null-hypothesis that trends and performance differences inferred from naïve-indirect comparisons and from direct comparisons/R...

Objective: Self-harm was classified to show forms like non-suicidal self injury and indirect risky behaviors and drug abuse. The aims of this study were to compare suicidal tendencies indexes and difficulty in emotion regulation skills in mixed groups of adolescents with direct and indirect forms of self-harm. Methods: In a casual-comparative design from population of delinquent adolescents ...

This study examined the role of error-type and working memory (WM) in effectiveness direct-metalinguistic indirect written corrective feedback (WCF) on self error-correction first-language writing. Fifty-one French first-year psychology students volunteered to participate experiment. They carried out a task after receiving WCF typographical, orthographic, grammatical, semantic errors. Results i...

conclusions accidents resulting in death, total disability, and partial disability impose a huge cost burden on society, whereas the employer will bear a relatively low cost. this is because of society’s health, treatment, and welfare systems available for treatment and rehabilitation of injured employees and their families. background occupational accidents represent one of the major problems ...

background: ubi 29-41 (a derivative of antimicrobial peptide ubiquicidin) labelled with 99mtc is reported to discriminate between bacterial infections and sterile inflammatory processes. in this study, three lyophilized kit were performed, one of them based on the direct labelling with only sncl2 as reducing agent , and other two based on 6- hydrazinopyridine-3-carboxylic acid (hynic) and trici...

How much can a constituency influence the power of its representative in the legislature? We develop a theoretical model of the constituency basis of legislator influence. The key players in the model are interest groups who may receive targeted transfers from the legislature. The model predicts that the amount of transfers that such groups receive is increasing in their ability to help a party...