نتایج جستجو برای: formalin induced pain

تعداد نتایج: 1217983  

Journal: :Journal of the Korea Academia-Industrial cooperation Society 2014

ژورنال: دانشور پزشکی 2016
جعفری, حسین, هادی پور, مهسا,

Background and Objective: Use of extremely low frequency magnetic field) ELF-MF (has been reported in increasing blood sugar, cholesterol, triglyceride and reduction of withdrawal syndrome signs of morphine. Since pain is one of the main considerations and usually analgesic drugs are not very useful and have side effects, therefore, the present project was carried out using formalin test to eva...

Journal: :British journal of anaesthesia 2014
J Yang H B Bae H G Ki J M Oh W M Kim H G Lee M H Yoon J I Choi

BACKGROUND Spinal serotonin (5-HT) receptors 3 (5-HT3R) and 7 (5-HT7R) are differentially involved in facilitatory or inhibitory descending modulation, respectively. Electrophysiological studies of the spinal cord have demonstrated that 5-HT3R is involved in nociception induced by intraplantar injection of formalin, but not carrageenan. In addition, depletion of spinal serotonin has been shown ...

M Javdan N Gheibi

Formalin as a chemical noxious stimulus evokes a biphasic pain that its second phase as a chronic inflammatory pain is similar to clinical pain. In this study, we used 40 NMRI male rats (250-300 g), and experiments were carried out considering ethical rules. Experiments were performed in normal and morphine addicted rats, the addiction was induced by Leung method. Behaviors of flinching and lic...

حجازیان, الهام السادات, حجازیان, سید حسن, صادقیان, محمد رضا,

Background and Objectives: Aerobic exercise or cardio is defined as a physical exercise that causes high oxygen consumption compared to the rest and conducted to increased cardiorespiratory intensity. Different substances, can inhibit pain occurred through opioids, histaminergic, and cholinergic receptors. This study was done to determine the role of aerobic exercise in pain by histamine rece...

Journal: :The Journal of pharmacology and experimental therapeutics 2011
Nian Gong Zhen-Yu Gao Yan-Chao Wang Xin-Yan Li Jin-Lu Huang Kenji Hashimoto Yong-Xiang Wang

We have found that mutation of D-amino acid oxidase (DAO) diminished formalin-induced tonic pain. The present research further studied the analgesic effects of a series of DAO inhibitors in this model. 5-Chlorobenzo[d]isoxazol-3-ol (CBIO), 4H-thieno[3,2-b]pyrrole-5-carboxylic acid (compound 8), 5-methylpyrazole-3-carboxylic acid (AS057278), sodium benzoate, and 4-nitro-3-pyrazole carboxylic aci...

2014
Meenakshi Chaudhary Veena Ghalaut

The study was done to find out the effect of Liraglutide on formalin induced tonic pain in obese rabbits. Rabbits were made obese by giving HFD (High fat diet) for 10 weeks. Tonic pain was induced with 5% formalin and it was observed that obese rabbits showed a significantly lesser pain score as compared to normal rabbits. Liraglutide (7μg/kg s.c.) was then given to both the group of rabbits fo...

Journal: :Pain physician 2017
Ya-Qun Zhao Hai-Yan Wang Jun-Bin Yin Yan Sun Yong Wang Jin-Chuan Liang Xiao-Ju Guo Ke Tang Yu-Tong Wang

The non-steroidal anti-inflammatory drug celecoxib has long been used for reducing pain, in spite of moderate gastrointestinal side effects. In previous studies, it has been shown that celecoxib can inhibit formalin-induced spontaneous pain and secondary hyperalgesia. Injecting formalin into a rodent's hind paw not only induces acute pain behaviors, but also produces long-lasting hyperalgesia. ...

2017
Roghaieh Khakpay Maryam Azaddar Fatemeh Khakpay Homeira Hatami Nemati

INTRODUCTION Beside its autonomic functions, the nucleus paragigantocellularis lateralis (LPGi) is involved in the descending pain modulation. 17β-Estradiol is a neuroactive steroid found in several brain areas such as LPGi. Intra-LPGi microinjection of 17β-estradiol can elicit the analgesic responses. 17β-Estradiol modulates nociception by binding to estrogenic receptors as well as allosteric ...

Journal: :Acta Amazonica 2022

ABSTRACT The oil of Caryocar villosum is used in Amazonian folk medicine to treat pain and inflammatory conditions. So, we assessed the anti-inflammatory antinociceptive properties ethanolic extract obtained from fruit peels this species. acetic acid-induced writhing, carrageenan-induced mechanical hyperalgesia, formalin, paw edema peritonitis tests were on mice. C. significantly inhibited numb...

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