نتایج جستجو برای: fractional release profile

تعداد نتایج: 488099  

Journal: :international journal of nonlinear analysis and applications 0
javad damirchi department of mathematics, faculty of mathematics, statistics and computer science, semnan university,semnan, iran

in this paper, we prove the existence and uniqueness results to the random fractional functional differential equations under assumptions more general than the lipschitz type condition. moreover, the distance between exact solution and appropriate solution, and the existence extremal solution of the problem is also considered.

2015
Paolo Grigolini Adam Svenkeson Malgorzata Turalska Bruce J. West Mirza Tanweer Beig

Fractional trajectories: Decorrelation versus friction Report Title The fundamental connection between fractional calculus and subordination processes is explored and affords a physical interpretation of a fractional trajectory, that being an average over an ensemble of stochastic trajectories. Heretofore what has been interpreted as intrinsic friction, a form of non-Markovian dissipation that ...

Journal: :iranian biomedical journal 0
بهاره عظیمی bahareh azimi پرویز نورپناه parviz nourpanah محمد ربیعی mohammad rabiee شهرام عرب shahram arbab

background: progress in the field of biology and biochemistry has led to the discovery of numerous bioactive peptides and proteins in the last few decades. delivery of therapeutic proteins/peptides has received a considerable amount of attention in recent years. methods: in this study, a two-step desolvation method was used to produce biodegradable hydrophilic gelatin nanoparticles (gnp) as a d...

Journal: :research in pharmaceutical sciences 0
s eskandari j varshosaz g akhavanfarid g hafizi

the most frequent adverse effects of indomethacin like other nsaids are gastro–intestinal and central nervous system disturbances. extended release or enteric release formulations minimize these symptoms. the objective of this study was to develop an extended release pellet formulation of indomethacin by the centrifugation (rotary fluid bed granulation) or powder layering method. layered, nonpa...

Journal: :iranian journal of pharmaceutical sciences 0
fatemah atyabi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran afsaneh mohammadi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran rassoul dinarvand department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran

the purpose of this study was to prepare and characterize nimodipine loaded microspheres using ethyl cellulose (ec) as a carrier polymer through an emulsion solvent evaporation method. these evaluations characterized the pattern of drug release from prepared microspheres. nimodipin loaded microspheres were prepared using an emulsification solvent evaporation method. the effect of process variab...

Mahsa Hedayatzadeh Mohammad Reza Avadi

The main aim of this study was preparation and evaluation of extended - release system ofthe anxiolytic substance. Alprazolam is a short-acting benzodiazepine with general propertiessimilar to those of diazepam. Our studies focused on development of extended drug deliverysystem based on Hydroxy Propyl Methyl Cellulose (HPMC 4000cps) as retard agent andPolyvinylpyrrolidone (PVP k30) as binder us...

ژورنال: دانشور پزشکی 2008
اصلانی, ابوالفضل , سجادی, سیدابراهیم , پیمانی, آتوسا ,

 Introduction: Psoriasis is a dermal disease with chronic recurrent and variable clinical schematic. Its cause isn’t known and its clinical symptoms are consist of cell proliferation, dermatitis, irritation and non predicted periods of heal and recurrent. Systemic and topical steroids are old treatments of psoriasis, but recently fumaric acid derivatives and cytotoxic drugs are prescribed. Beca...

Journal: :iranian journal of pharmaceutical research 0
n bhabani shankar r prasant kumar n udaya kumar b benoy bratac

the present study concerned with the development and characterization of metronidazole microcapsules prepared by thermal change method using different ratios (1:1, 1:2 and 1:4) of ethyl cellulose in order to select the best microcapsule formulation with a good encapsulation efficiency and drug release profile. the obtained microcapsules were discrete, spherical with free flowing properties and ...

Abbas Akhgari, Fatemeh Sadeghi, Hadi Afrasiabi Garekani Mohammad Reza Abbaspour Roshanak Dolatabadi,

Objective(s): This study evaluates the effect of substitution of microcrystalline cellulose (MCC) with ethylcellulose (EC) on mechanical and release characteristics of theophylline pellets. Materials and Methods: The effect of addition of EC was investigated on characteristics of pellets with varying drug content prepared by extrusion-spheronization. Also the effect of type of granulating liqui...

2011

Purpose: The objective of this study was to prepare Propranolol Hydrochloride controlled release matrix tablets and to investigate the effect of the polymer blends and the polymer concentration on drug release. Method: Propranolol Hydrochloride controlled release matrix tablets were prepared by direct compression technique. Hydroxypropylmethylcellulose K15M (HPMC K15M) and Carbopol 934P were us...

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