normal 0 false false false en-us x-none ar-sa background: p revious studies confirmed that neural gene expression in embryonic stem cells (esc) could influence by chemical compounds through stimulating apoptotic pathway. we aimed to use escs-derived neural cells by embryoid body formation as an in vitro model for determination of neural gene expression changes in groups that treated by sera fro...

background: acute myeloid leukemia (aml) is known as one of the most common leukemia among adults. environmental and different genetic factors affect disease process, prognosis and treatment. among different genetic factors npm1, flt3, mll and baalc genes are the most effective on patient's survival rate. the aim of this study was to assess amount of baalc gene expression in aml patients, and i...

bovine ephemeral fever (bef) is an acute epidemic disease in cattle and water buffalo, spanning tropical and subtropical zones of asia, australia, and africa. in recent years, bef has been distributed in many provinces of iran and caused economic losses. in this study the sequence encoding the g1 epitope of bovine ephemeral fever virus (befv) g glycoprotein was amplified by pcr, ligated into th...

introduction: kainic acid (ka) induces neuropathological changes in specific regions of the mouse hippocampus comparable to changes seen in patients with chronic temporal lobe epilepsy (tle). according to different studies, the expression of a number of genes are altered in the adult rat hippocampus after status epilepticus (se) induced by ka. this study aimed to quantitatively evaluate changes...

background: after radiation therapy (rt), some health hazards including dna damages may occur where melatonin can play a protective role due to free radical generation. on the other hand, serious accidental overexposures may occur during rt due to nuclear accidents which necessitate the need for study on exposure to high-dose radiations during treatments. objective: the aim of this study was to...

objective(s): the link between a hyperglycemic intrauterine environment and the development of diabetes later in life has been observed in offspring exposed to gestational diabetes mellitus (gdm), but the underlying mechanisms for this phenomenon are still not clear. reduced β-cells mass is a determinant in the development of diabetes (type 1 and type 2 diabetes). some recent studies have provi...

background: the aim of this study was to detect the prognostic significance of survivin level and the expression of total p53 in acute lymphoblastic leukemia (all) and its correlation to patients' outcome. methods: sixty two children newly diagnosed with acute lymphoblastic leukemia were treated with chemotherapy and followed up for 2 years or until death. twenty apparently healthy volunteers w...