Parasympathetic regulation of heart rate through the vagus nerve—often measured as resting respiratory sinus arrhythmia or cardiac vagal tone (CVT)—is a key biological correlate of psychological well-being. However, recent theorizing has suggested that many biological and psychological processes can become maladaptive when they reach extreme levels. This raises the possibility that CVT might no...

A continuously variable transmission (CVT) consisting of slider-cranks, solid cams and non-invertible mechanisms is discussed in this paper. The conventional CVTs are mainly classified as belt-types or toroidal types conduction mechanisms. Basically, these composed frictional components. However, the proposed CVT paper does not have any special friction conductions. Friction force which being o...

Periodic centroidal Voronoi tessellation (CVT) in hyperbolic space provides a nice theoretical framework for computing the constrained CVT on high-genus (genus > 1) surfaces. This paper addresses two computational issues related to such hyperbolic CVT framework: (1) efficient reduction of unnecessary site copies in neighbor domains on the universal covering space, based on two special rules; (2...

The cytoplasm-to-vacuole targeting (Cvt) pathway of Saccharomyces cerevisiae delivers aminopeptidase I (Ape1) from the cytosol to the vacuole, bypassing the normal secretory route. The Cvt pathway, although well-studied, was known only in S. cerevisiae. We demonstrate its existence in the methylotrophic yeast, Pichia pastoris, where it also delivers P. pastoris Ape1 (PpApe1) to the vacuole. Mos...

OBJECTIVE To compare the hyoid bone position between cleft lip/palate and normal patients. STUDY DESIGN Cross-sectional analytical study. PLACE AND DURATION OF STUDY Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIEKIOHS), Dow University of Health Sciences (DUHS), Karachi, from March 2012 to February 2013. METHODOLOGY The sample for this study consisted of total 68 subjects a...

This paper deals with electromagnetic design and 2-D (two-dimensional) magnetic field analysis of novel low force ripple linear switched reluctance (LSR) motor. The configuration that has been presented here has a higher number of rotor poles than stator poles, and the purpose of this configuration is to improve the force ripple, which is the weak point of LSRMs. In order to illustrate the ...

The advent of high speed microcomputers and available software has made possible the calculation of magnetic fields and torques of brushless DC motors. In particular, the Boundary Element Method (BEM) has shown to be an efficient tool for the design of these motors. This paper explains the BEM approach and addresses the key concerns facing the design engineer using such software, i.e. the ease ...

We show that a system of parallel D3 branes near a conifold singularity can be mapped onto an intersecting configuration of orthogonal branes in type IIA string theory. Using this brane configuration, we analyze the Higgs moduli space of the associated field theory. The dimension of the Higgs moduli space is computed from a geometrical analysis of the conifold singularity. Our results provide e...

Several potent and selective A2A adenosine receptor agonists are currently available. These compounds have a high affinity for the A2A receptor and a long duration of action. However, in situations where a short duration of action is desired, currently available A2A receptor agonists are less than ideal. From a series of recently synthesized A2A receptor agonists, two agonists (CVT-3146 and CVT...