Nonreceptor tyrosine kinases have an increasingly appreciated role in cardiac injury and protection. To investigate novel tasks for members of the Tec family of nonreceptor tyrosine kinases in cardiac phenotype, we examined the behavior of the Tec isoform in myocardial ischemic injury. Ischemia-reperfusion, but not cardiac protective agents, induced altered intracellular localization of Tec, hi...

The tyrosine kinase Tec belongs to a new group of structurally related nonreceptor tyrosine kinases that also includes Btk and Itk. Previous studies have suggested that these kinases have lineage-specific roles, with Tec being involved mainly in the regulation of cytokine-mediated myeloid cell growth and differentiation. In this study, we investigated expression and activation of Tec in human B...

The International Reference Ionosphere (IRI) is an empirical model widely used to describe ionospheric characteristics. In the previous research, high-precision total electron content (TEC) data derived from global navigation satellite system (GNSS) were adjust index IG12 as a driving parameter in standard IRI model; thus, errors between IRI-TEC and GNSS-TEC minimized, was calibrated by modifyi...

This article experimentally investigates the thermal performance of thermoelectric air-cooling module which comprises a thermoelectric cooler (TEC) and an air-cooling heat sink. The influences of input current and heat load are determined. And performances under each situation are quantified by thermal resistance analysis. Since TEC generates Joule heat, this nature makes construction of therma...

Exposure of renal tubular epithelial cells (TEC) to IFN-gamma/TNF-alpha leads to Fas/FasL-mediated self-injury, which contributes to allograft rejection. Indoleamine 2,3-dioxygenase (IDO) converts tryptophan to N-formyl-kynurenine and contributes to immune privilege in tissues by increasing Fas-mediated T cell apoptosis. However, renal expression of IDO and its role in promoting Fas-mediated TE...

background road traffic accidents and their related deaths have become a major concern, particularly in developing countries. iran has adopted a series of policies and interventions to control the high number of accidents occurring over the past few years. in this study we used a time series model to understand the trend of accidents, and ascertain the viability of applying arima models on data...

sulfur dioxide has two important sources in the atmosphere and this is why most of scientists believe in a geographic split in the globe. power plants, major emitter of so2, are located in north hemisphere such as in russia, china, canada and the usa. in south hemisphere, phytoplankton produces a massive amount of dimethyl sulfide (dms) and dimethyl disulfide (dmds). then these types of reduced...

in the management of river basins, prediction of river water quality is essential to maintain water quality within standard limits. this study performed a time-series analysis of the prediction of chlorine concentration and electrical conductivity time series data for the period of 1991-2005 from sefidrood river in northern iran. the seasonal prediction of chlorine and electrical conductivity t...