BACKGROUND Detecting paroxysmal atrial fibrillation (PAF) in patients with cerebral ischemia is challenging. Frequent premature atrial complexes (PAC/h) and the longest supraventricular run on 24-h-Holter (SV-run(24 h)), summarised as excessive supraventricular ectopic activity (ESVEA), may help selecting patients for extended ECG-monitoring, especially in combination with echocardiographic mar...

Hyphessobrycon klausannisp. n. is described from small drainages of the upper Guaviare River (Orinoco River Basin) in Colombia. It differs from all congeners by having a wide, conspicuous, dark lateral stripe extending from the anterior margin of the eye across the body and continued through the middle caudal-fin rays, and that covers (vertically) three or four horizontal scale rows. It also di...

The aim of this study was to investigate the influence of the duration of bladder overdistention (DOBO) on kidney structure and function in rats. Bladder overdistention was induced in male Sprague-Dawley rats by an infusion of saline. Forty rats were divided into five groups: DOBO 1, 2, 4 or 8 h groups and the control. Renal function was evaluated using serum creatinine (SCr) and blood urea nit...

OBJECTIVE To compare pharmacokinetics (PK) and pharmacodynamics (PD) of insulin glargine in type 2 diabetes mellitus (T2DM) after evening versus morning administration. RESEARCH DESIGN AND METHODS Ten T2DM insulin-treated persons were studied during 24-h euglycemic glucose clamp, after glargine injection (0.4 units/kg s.c.), either in the evening (2200 h) or the morning (1000 h). RESULTS Th...

OBJECTIVE We evaluated the effect of maternal administration of ampicillin/sulbactam on colonization and bacteremia in newborn rabbits after intracervical inoculation of mothers with group B streptococci (GBS). METHODS New Zealand white rabbits on day 30 of a 31-day gestation were inoculated intracervically with 10(4)-10(5) colony forming units (cfu) GBS. Two hours after inoculation mothers r...

OBJECTIVE Consuming smaller, more frequent meals is often advocated as a means of controlling body weight, but studies demonstrating a mechanistic effect of this practice on factors associated with body weight regulation are lacking. The purpose of this study was to compare the effect of consuming three (3M) vs. six meals (6M) per day on 24-h fat oxidation and subjective ratings of hunger. DE...

Ninety-six crossbred barrows and gilts weighing 90 +/- .67 kg were used during a 21-d study to determine the effects of a hot, diurnal temperature (H; 22.5 to 35 degrees C) compared with a constant, thermoneutral temperature (TN; 20 degrees C) and the effects of sex (barrows vs gilts) on performance. A secondary objective included the determination of weight loss as a result of a 24-h fast imme...

There is no randomized study carried out in order to compare their pharmacokinetic parameters although midazolam, as a sedative, has been widely administered via continuous infusion as well as intermittent bolus doses in mechanically ventilated critically ill patients. We prospectively investigated the effect of these two principal methods on pharmacokinetic parameters in 23 of mentioned patien...