نتایج جستجو برای: hek293 cells cytotoxic effects
تعداد نتایج: 2751838 فیلتر نتایج به سال:
sophora pachycarpa schrenk ex c.a.mey. belongs to the family fabaceae. some species of the genus sophora have shown to possess anti-proliferative and apoptosis-inducing activites in cancer cells. however, there is no available information addressing this effect in s. pachycarpa. here, we investigated the cytotoxic effects of methanol extract and different fractions obtained from s. pachycarpa r...
Activation of gonadotropin-releasing hormone (GnRH) receptors inhibits proliferation of transformed cells derived from reproductive tissues and in transfected cell lines. Hence, GnRH receptors represent a therapeutic target for direct action of GnRH analogues on certain proliferating cells. However, more cell biological data are required to develop this particular application of GnRH analogues....
Background and purpose: Tumors are one of the most important threats to human life and improving the drugs used in their treatment is always necessary. Isatin is found in many plants and also synthesized through different methods. Many studies have been done on Isatin ring, including the construction of Dibromoisatin derivatives that exhibit anti-cancer effects. The aim of this stud...
Cancer is a disease that invades the lives of millions people each year. Chemotherapy currently most effective treatment however resulting in many adverse effects to human body. Alternative treatments are being explored overcome this obstacle. Peptides possess radical scavenging activity and bioactive properties can be advantageous prevention chronic diseases. In study, Lablab purpureus isolate...
Background: Studies have shown that sexual steroids can affect metastasis in cancer cells of nervous system at cellular and molecular level; however, the cellular and molecular mechanism of sexual steroids action on metastasis in cancer cells of nervous system is unclear in many cases. This study aimed at investigating the effects of cytotoxic dose of testosterone, progesterone and estradiol on...
EVALUATION OF THE EFFECTS IBUPROFEN CYTOTOXIC DOSE ON EXPRESSION LEVEL EXTRACELLULAR MATRIX DEGRADING MMP-9 AND ANTI-METASTASIS NM23 GENES IN CERVICAL CANCER CELLS
Activation of gonadotropin-releasing hormone (GnRH) receptors inhibits proliferation of transformed cells derived from reproductive tissues and in transfected cell lines. Hence, GnRH receptors represent a therapeutic target for direct action of GnRH analogues on certain proliferating cells. However, more cell biological data are required to develop this particular application of GnRH analogues....
background: one of the major paths for drug development is the study of bioactivities of natural products. therefore, the aim of this study was to compare the cytotoxic effects of aqueous extract of whole cuscuta chinensis lam., which is a traditional medicinal herb commonly used in iran and other oriental countries, on the human caucasian acute lymphoblastic leukemia (ccrf-cem) and another hum...
conclusions b. oleracea demonstrated similar anti-inflammatory properties to omeprazole in rats with gerd. however, omeprazole also demonstrated genotoxic and cytotoxic effects in rats without gerd. results rats with gerd developed esophagitis and esophageal squamous cell carcinoma. b. oleracea and omeprazole-treated gerd rats presented significantly decreased inflammation in relation to non-tr...
Objective(s):Perovskia abrotanoides Kar., from family Lamiaceae, is a little known medicinal plant growing in various regions of Iran. In the present study, cryptotanshinone (CT), tanshinone 2A (Tan2A), and hydroxycryptotanshinone (HCT) were isolated and purified from the roots of P. abrotanoides. In addition, cytotoxic and apoptotic effects of total root extract (TE) and three purified tanshin...
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