Studies were carried out during the neonatal period in three infants with D1 trisomy syndrome to measure the proportion of fetal and adult hemoglobin being synthesized. These values were compared on the one hand to those previously reported from samples obtained from cord blood of normal newborn infants ranging from 25 to 43 wk gestation, and on the other hand to those values determined in crit...

The purpose of this study was to determine changes in hematological and plasma indices of Common Carp Cyprinus carpio with regard to age, sex and hormonal treatment. Sixty fish were used to assess the age factor. Also, 20 fish including female and male were assigned to determine blood indices with regard to sex and hormonal treatment. The pituitary gland extract was used as hormone for males an...

One hundred and seventeen patients with severe aplastic anemia (SAA) were treated at our institution between 1976 and 1990 with antilymphocyte globulin (ALG) therapy. Seventy-nine (68%) are alive and probability of survival at 14 years, according to Kaplan and Meier, is 62% +/- 12%. Twenty-six patients developed a late clonal complication: 11 had a myelodysplastic syndrome (MDS) and 17 had paro...

Studies were carried out during the neonatal period in three infants with D1 trisomy syndrome to measure the proportion of fetal and adult hemoglobin being synthesized. These values were compared on the one hand to those previously reported from samples obtained from cord blood of normal newborn infants ranging from 25 to 43 wk gestation, and on the other hand to those values determined in crit...

Dear Editor, Reports on the analytical evaluation of capillary electrophoresis (CE) for glycated hemoglobin (HbA1c) measurement have already been published [1]. There have been several recent reports concerning the impact of the presence of hemoglobin variants on HbA1c measurement with the CE method. One study focused on the analytical interference of some hemoglobin variants [2], demonstrating...

Bovine hemoglobin/Amino acid/Oxygen binding capacity In this paper the structural and functional changes of gamma irradiated bovine hemoglobin are presented. Aqueous solutions/1%/of HbO2 were irradiated in air with doses ranging from 1 to 4 Mrad. Isoelectric focusing indicated change of the charge of irradiated hemoglobin. The isoelectric point of hemoglobin was displaced towards more acid valu...

T O optimize the planning of blood donations but also to continue motivating the volunteers it is important to streamline the practical organization of the timing of donations. While donors are asked to return for donation after a suitable period, still a relevant proportion of blood donors is deferred from donation each year due to a too low hemoglobin level. Rejection of donation may demotiva...

Patients with thalassemia major often report that they do not maintain their usual pretransfusion hemoglobin concentration during the summer season. We collected 3977 pretransfusion hemoglobin values, amount of blood transfused, and intertransfusion intervals for 94 patients with thalassemia major from 4 centers worldwide. We also assessed the hematocrits of blood donors, the hemoglobin content...

We investigated the effect of temperature, variant hemoglobins, and hyperlipidemia on determination of glycosylated hemoglobin by an electrophoretic method (Clin. Chem. 26: 1598-1602, 1980). We found that: (a) temperature variations ranging from 4 to 30 degrees C were without effect on results obtained by electrophoresis; (b) concurrent determination of glycosylated hemoglobin by electrophoresi...