BACKGROUND We have observed that dry eye redness is characterized by a prominence of fine horizontal conjunctival vessels in the exposed ocular surface of the interpalpebral fissure, and have incorporated this feature into the grading of redness in clinical studies of dry eye. AIM To develop an automated method of grading dry eye-associated ocular redness in order to expand on the clinical gr...

buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. a mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.in this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...

Starting from second-order conditions for C scalar unconstrained optimization problems described in terms of the second-order Dini directional derivative, we pose the problem, whether similar conditions for C vector optimization problems can be derived. We define second-order Dini directional derivatives for vector functions and apply them to formulate such conditions as a Conjecture. The proof...

The non-hydrostatic (NH) compressible Euler equations for dry atmosphere were solved in a simplified two-dimensional (2-D) slice framework employing a spectral element method (SEM) for the horizontal discretization and a finite difference method (FDM) for the vertical discretization. By using horizontal SEM, which decomposes the physical domain into smaller pieces with a small communication ste...

A universal approach by Laplace transform to the variational iteration method for fractional derivatives with the nonsingular kernel is presented; in particular, the Caputo-Fabrizio fractional derivative and the Atangana-Baleanu fractional derivative with the non-singular kernel is considered. The analysis elaborated for both non-singular kernel derivatives is shown the necessity of considering...

abstract : horizontal root fractures in permanent teeth are uncommon injuries among dental traumas. the principle of treating horizontal root fractures of permanent teeth is repositioning and fixation of fractured segment. diagnosis of tooth fractures based on radiographic findings and the fracture healing process are affected by factors before and after injury. the present case reports the tre...

The modification of the Clarke generalized subdiNerentia1 due to Michel and Penot is a useful tool in determining differentiability properties for certain classes of real functions on a normed linear space. The Glteaux differentiability of any real function can be deduced from the GBteaux differentiability of the norm if the function has a directional derivative which attains a constant related...

In this study, a derivative method is applied for the determination of dye concentration in fabrics dyed with tricomponent dye mixtures. The reflectance of spectra of the samples were recorded between 400 and 700 nm. Initially, the obtained (K/S) spectra were divided by the spectrum of a standard sample dyed with two of the components in the ternary mixture and the derivative spectra were calcu...

We investigate the selective forces that promote the emergence of modularity in nature. We demonstrate the spontaneous emergence of modularity in a population of individuals that evolve in a changing environment. We show that the level of modularity correlates with the rapidity and severity of environmental change. The modularity arises as a synergistic response to the noise in the environment ...

Generally, the finite element method is a powerful procedure for analysis of tall buildings. Yet, it should be noted that there are some problems in the application of many finite elements to the analysis of tall building structures. The presence of artificial flexure and parasitic shear effects in many lower order plane stress and membrane elements, cause the numerical procedure to converge in...