Abstract Context Developmental disorders of the pituitary gland leading to congenital hypopituitarism can either be isolated or associated with extrapituitary abnormalities (syndromic hypopituitarism). A large number syndromic cases are linked mutations in transcription factors. The forkhead box A2 (FOXA2) is a factor that plays key role central nervous system, foregut, and pancreatic developme...

Lymphocytic hypophysitis represents a difficult diagnostic and therapeutic challenge. The clinical presentation of this inflammatory condition may mimic that pituitary adenoma with apoplexy. We report case 45 years old male patient acute adrenal crisis complicating chronic hypopituitarism secondary to lymphocytic hypophysitis. was managed acutely high dose steroids supportive measures, is curre...