Objective(s):The present study was undertaken to determine the effects of acute exposure to malathion on oxidative stress and cytotoxic potential of anticholinesterase insecticide, malathion in reproductive toxicology of adolescent male mice. Materials and Methods: Thirty two adolescent male mice at pubertal age were treated with 500 mg/kg body weight (BW) of malathion for three days. After ex...

Ageing is a complex process and understanding the factors affecting ageing and end points of study design are complicated and needs to be addressed through various strategies. In this study we have evaluated the ageing process on exposure to low doses of dichlorvos an organophosphorous insecticide used in controlling crop pests and also used in warfare agent and elucidated the various degrees o...

Introduction: The mosquito species of Ae. aegypti is a vector arthropod-borne diseases such as dengue haemorrhagic fever. Acetylcholinesterase (AChE) enzyme in that encoded by the ace-1 gene. Damage gene target insecticide lead to loss normal structure and function AChE. However, damage remains uncharacterised. main aim this study was find out point mutations larvae treated with methanolic extr...

Synthetic fibers released from sewage sludge and tire particles traffic are among the most common types of microplastics in soil. In soil, may interact with chemicals, such as plant protection products used agriculture. Most studies on interactions chemicals focused aquatic environments only few addressed soil arthropods. To increase understanding combined effects arthropods, we studied polyest...

BACKGROUND & AIMS There have been many studies on plasma butyrylcholinesterase in liver dysfunction. However, no data is available about acetylcholinesterase in human cirrhosis, although profound changes have been described in cirrhotic rat models. METHODS Human serum and liver acetylcholinesterase and its molecular forms were determined enzymatically, after butyrylcholinesterase immunodeplet...

The short and long term effects of chromium toxicity on brain catecholamines and acetylcholinesterase levels were investigated. Rats were injected daily with varying amounts of chromium. The short term (2 h) administration of chromium (8 mmol/kg) reduced catecholamines level of cerebellum, mid-brain and brain-cortex by 22.8, 19.4 and 21.2% respectively. Acetylcholinesterase activity was also re...