نتایج جستجو برای: interferon gamma 1b
تعداد نتایج: 185145 فیلتر نتایج به سال:
results almost 8% of the personnel showed positive tst (over 10 mm) reaction while 29% of them had considerable t - cell reactivity against ppd in elispot assays. however, the esat - 6 reactivity was found only in one case of hcws. no correlation was found between the patterns of the reactions and the age or the duration of the employment or previous vaccination history of the participants. the...
Background and Objectives: Interferon-gamma is an important cytokine, which facilitates immunity against intracellular pathogens. Several factors, including genetic variations of cytokine-producing genes have been shown to influence the progression and severity of Hepatitis C virus (HCV) infection. Methods: Between January and D...
The intramolecular aminomercuration of gamma-alkenylamines 1a, 1b and 4 was shown to afford the 5-endo-trig cyclized product exclusively in good yield. The utility of pyrrolidine derivatives thus obtained from D-glucose derived gamma-alkenylamines 1a and 1b was demonstrated in the synthesis of 1-deoxycastanospermine (3a) and 1-deoxy-8a-epi- castanospermine (3b).
human interferon β (inf-β) is a member of cytokines family which different studies have shown its immunomodulatory and antiviral activities. in this study an expression vector was designed and constructed for expression of human inf-β-1b either in shake flasks and bench top bioreactor. the designed vector was constructed based upon pet-25b(+) with t7 promoter. recombinant human beta interferon ...
Salicylate enhanced the interferon-gamma-dependent activation of two transcription factors in a murine macrophage cell line: signal transducer and activator of transcription (STAT)1 and interferon-gamma-responsive factor 1. Salicylate alone did not activate these transcription factors. This enhancement was reflected by increased DNA-binding activities and was the consequence of prolonged tyrosi...
BACKGROUND Interferon beta treatment is only partially effective in multiple sclerosis (MS) suggesting a potential role for adjunctive therapies. Retinoids can augment the clinical efficacy of type 1 interferons in patients with cancer. We reasoned that the same might hold in MS. Interferon beta-1b added to peripheral blood mononuclear cells in vitro partially reverses the CD8 suppressor cell d...
PURPOSE To study the presence of muscarinic and alpha- and beta-adrenergic receptors in a normal human conjunctival epithelial (IOBA-NHC) cell line. METHODS Neurotransmitter receptors were determined in IOBA-NHC cells by flow cytometry, immunofluorescence, and Western blot analysis. Antibodies to M(1)-, M(2)-, and M(3)-muscarinic and to alpha(1A)-, alpha(1B)-, alpha(1D)-, alpha(2A)-, alpha(2B...
Background: One in every 250 newborns is exposed to antiepileptic drugs, inutero .The risk of congenital malformations in newborns, prenatally exposed to antiepileptic drugs (AEDs), is around 5% which is 2 to 2.5 times that of general population; while carbamazepine (CBZ) and valproate (VPA) still provide the treatment of choice in most forms of epilepsy, being efficacious in approximately two-...
atopic dermatitis (ad) is a heterogeneous disease with regard to clinical phenotype and natural history. we investigated t cell subtypes and cytokine responses in peripheral blood and skin lesions of ad patients with various sensitivities. immunological studies were performed in 27 subjects: 9 house dust mite (hdm)-sensitized; 6 subjects with sensitizations other than hdm; 7 non-allergic ad pat...
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