Several molecular epidemiological studies have been conducted to examine the association between low-density lipoprotein receptor-related proteins (LRP5) Ala1330Val polymorphism and fracture; however, the conclusions remained controversial. We therefore performed an extensive meta-analysis on 10 published studies with 184479 subjects. Electronic databases, including PubMed, Excerpta Medica Data...

In recent years, there has been a surge in the development of finite-element (FE) models aimed at testing biological hypotheses. For example, recent modelling efforts suggested that the beak in Darwin's finches probably evolved in response to fracture avoidance. However, knowledge of the material properties of the structures involved is crucial for any model. For many biological structures, the...

BACKGROUND Interleukin-6 (IL6) -174C/G polymorphism was suggested to be associated with fracture risk. However, the results were inconsistent. Thus, we did a meta-analysis. METHODS Reported studies were searched from online electronic databases of Pubmed, EMBASE, Chinese National Knowledge Infrastructure (CNKI). The odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were calcu...

This paper presents a novel approach to achieving the goals of data envelopment analysis in the process of reconstruction and integration of decision-making units by using multiple objective linear programming. In this regard, first, we review inverse data envelopment analysis models for data reconstruction and integration. We present a model with multi-objective linear programming structure in...

This paper introduces a comprehensive C++ software package, HatchFrac, for stochastic modeling of fracture networks in two and three dimensions. The inverse cumulative distribution function (CDF) acceptance–rejection methods are applied to generate random variables from the distributions commonly used discrete network (DFN) modeling. multilayer perceptron (MLP) machine learning approach, combin...