BACKGROUND Glaucomatous neuropathy is a type of cell death due to apoptosis. The p53 gene is one of the regulatory genes of apoptosis. Recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (POAG) has been studied in some ethnic groups. This study is the first association analysis of POAG and p53 codon 72 polymorphism in Iranian patients....

Introduction: The aim of this study was to investigate the prevalence of stylohyoid ligament complex elongation in a group of Iranian patients using digital panoramic radiographs. Methods: Panoramic radiographs of 1211 patients (684 females and 527 males) referred to the dental school of Hamadan university of medical science were selected from 2011 to 2013. The stylohyoid ligament complexes wer...

Ankylosing spondylitis (AS) is an inflammatory arthritis, which affects mainly spine and sacroiliac joints. According to recent studies, ERAP1 is the second most common candidate gene for AS susceptibility after HLA-B27. The aim of this study was to determine the association of ERAP1 gene polymorphisms with AS in Iranian population.The study group comprised 387 Iranian AS patients and 316 healt...

BACKGROUND The Iranian Ministry of Health and Medical Education published a 'Patient's Bill of Rights' in 2001. AIM To gain insight into the perception and practice of patients' rights in Iran. This paper reports on Iranian nurses' and physicians' perceptions and lived experiences of respecting patients' rights. METHODS A purposeful sample of eight nurses and five physicians working in a ce...

Breast cancer is the most common cancer in Iran. In the recent years an upward trend has been observed in the Iranian population. Early detection by molecular approaches may reduce breast cancer morbidity and mortality. We provided consultation to 3,782 women diagnosed with early onset breast cancer during the past 15 years (1999-2014). To establish a data set for BRCA gene alterations of the I...

BACKGROUND Some Iranian pilgrims are referred to Iran because of catching a new disease or exacerbation of their disease during the Hajj ceremony. These diseases need prolonged and specialized treatments. Investigation of the reasons led to their return to Iran is useful and effective in policy-making and planning of preventive health services. OBJECTIVES This study aimed to investigate the c...

BACKGROUND Low-back pain is one of the most common human morbidities worldwide, which is damaging individually, socially and economically. Recent studies have shown that its prevalence is rising. Most of the low-back pains are non-specific though specific ones need more complicated and more expensive treatments. Sciatica or lumbar radiculopathy is one of these specific low-back pains and is exp...

Systemic Lupus Erythematosus (SLE) is a heterogeneous complex relapsing-remitting autoimmune disease. The role of genetics is obvious in predisposition of the disease. Several Single Nucleotide Polymorphisms (SNPs) in ETS1 and WDFY4 showed association with SLE in genome-wide association studies. The aim of this study was to examine the association of the SNPs in ETS1 and WDFY4 genes with SLE in...

OBJECTIVE The purpose of the study was to examine relationships between death anxiety and quality of life (QOL) parameters of patients with cancer in the Iranian sociocultural context. METHODS A descriptive, correlational methodology was used. The sample included 330 patients. Demographics, health information, religious behaviors, death anxiety, and QOL data were collected. RESULTS Overall ...