Cell-swelling, induced by a hyposmotic shock, activates the release of taurine from lactating rat mammary tissue explants. The degree of stimulation of taurine efflux was dependent upon the extent of cell-swelling. Volume-sensitive taurine release was attenuated by the anion transport inhibitors NPPB, DIOA, DIDS, niflumate, flufenamate, mefenamate and diiodosalicylate but not by salicylate. Cel...

Impaired onset of maternal behavior in first generation rat dams was previously correlated with rearing by cocaine-treated dams and prenatal cocaine exposure. Pup-induced maternal behavior in non-lactating rats has not been examined with regard to cocaine exposure and rearing conditions. First generation male and female juveniles and young adult males reared by cocaine-treated or control dams a...

Fatty acid synthetase was isolated from transplantable mammary adenocarcinomas carried by C3H mice. Comparison of physicochemical and immunological properties of this enzyme with those of the fatty acid synthetase isolated from normal glands of lactating C3H mice indicates that the enzymes are similar in all respects. The products of the purified fatty acid synthetase from normal and neoplastic...

a total of 153 samples of milk were collected from one to none months lactating mothers age 17 to 44 years. the protein, total nitrogen, fat, lactose and calcium content 0f these milks were determined. marked individual variation existed in the protein lactose and fat content of the milks, which was in agreement with finding of other investigators. a gradual decrease was noticed in the protein ...

acterization of the transplantable lactating mammary tumor R3230AB of the Fischer rat was recently reported (11). During that investigation, a slow growing variant neoplastic line occurred in 1 of the animals in which the mammary adenocarcinoma had been implanted for main tenance purposes. Examination of this subline revealed a mammary carcinoma which was comprised primarily of epithelial cells...

OBJECTIVE To assess the iodine nutrition and thyroid function of pregnant women, lactating women and infants residing in areas where the Universal Salt Iodization program is in place. METHODS Pregnant women, lactating women and infants were selected randomly in the regions where iodized salt coverage rate is more than 90% since 2000. Urine iodine levels of pregnant woman, lactating woman and ...

The isolation of acetyl-CoA carboxylase from lactating rat mammary glands is described. A procedure was used which differs significantly from those employed by others who have isolated this enzyme from animal tissues. The purified enzyme catalyzes the carboxylation of 5.5 pmoles of acetylCoA per min per mg of protein under optimum assay conditions. Apparent K, values were determined for acetyl-...