Plasma lipoprotein[a] (Lp[a]) is associated with atherogenesis and thrombogenesis. We examined how plasma Lp[a] in healthy young men was affected by fats high in stearic (C18), palmitic (C16), and lauric+myristic (C12+ C14) acid (experiment I, 15 subjects), and by fats high in myristic (C14) and palmitic (C16) acid (experiment II, 12 subjects). Strictly controlled isocaloric diets with 36% of e...

A new member of the cytochrome P450 (CYP) 4A subfamily (CYP4A21) was recently cloned by PCR from pig liver [Lundell, Hansson, and Wikvall (2001) J. Biol. Chem. 276, 9606-9612]. This enzyme does not catalyse omega- or (omega-1)-hydroxylation of lauric acid, the model substrate for CYP4A enzymes. Instead, CYP4A21 participates in bile acid biosynthesis in the pig. Extensive studies, primarily cond...

The susceptibility of Candida albicans to several fatty acids and their 1-monoglycerides was tested with a short inactivation time, and ultrathin sections were studied by transmission electron microscopy (TEM) after treatment with capric acid. The results show that capric acid, a 10-carbon saturated fatty acid, causes the fastest and most effective killing of all three strains of C. albicans te...

The control of the crystalline structure and shape (crystal habit) nanoparticles (NPs) is key to controlling their physical chemical properties. Among different metals, crystallogenesis ruthenium NPs has been less studied, until recently, Ru NP crystal morphology have considered as presenting versatility than face-centered cubic (fcc) metals platinum group. Here, we show that while hydrogenatio...

Arachidonic acid is omega-hydroxylated to 20-hydroxyeicosatetraenoic acid (20-HETE), which has effects on vasoactivity and renal tubular transport and has been implicated in the regulation of blood pressure. Cytochrome p450 (p450) 4A isoforms are generally considered the major arachidonic acid omega-hydroxylases; however, little is known about the role of rat CYP4F isoforms in 20-HETE formation...

Komak bean (Lablab purpureus (L.) Sweet) belongs to the family Fabaceae and subfamily Papilionidae. Komam is cultivated by people for consumption as an additional food source. Informationabout active compound content of komak needed a reference in utilization komak. This research aims determine compounds contained seed Sweet). study used GC-MS analysis components seed. Based on result, Beak Bon...