نتایج جستجو برای: ldh
تعداد نتایج: 8813 فیلتر نتایج به سال:
D-Lactate is oxidized by two classes of D-lactate dehydrogenase (D-LDH), namely, NAD-dependent and NAD-independent D-LDHs. Little is known about the characteristics and biological functions of D-LDHs in rice. In this study, a functional NAD-independent D-LDH (LOC_Os07g06890) was identified in rice, as a result of alternative splicing events. Characterization of the expression profile, subcellul...
A lactate dehydrogenase-deficient (Ldh-) mutant of a human isolate of Streptococcus mutans serotype c was tested in a gnotobiotic rat caries model. Compared with the wild-type Ldh-positive (Ldh+) strains, it was significantly (alpha less than or equal to 0.005) less cariogenic in experiments with two different sublines of Sprague-Dawley rats. The Ldh- mutant strain 044 colonized the oral cavity...
We prepared stable homogeneous suspensions with layered double hydroxide (LDH) nanoparticles for in vitro gene delivery tests. The viability of HEK 293T cells in the presence of LDH nanoparticles at different concentrations was investigated. This revealed 50% cell viability at 500 microg/mL of LDH nanoparticles that is much higher than 50-100 microg/mL used for the delivery tests. The supercoil...
بیوچار و هیدروچار مواد جامد کربنی هستند که از کربونیزهشدن زیست‌توده‌های آلی تولید می‌شوند. بیوچار با گرماکافت زیست‌توده‌های خشک اما هیدروچار با کربونیزهشدن گرمآبی زیست‌توده‌های خشک و یا مرطوب تولید میشود. در این پژوهش، بعد از تولید بیوچار و هیدروچار از چوب سیب، با ترسیب ذرات هیدروکسید دوگانه لایه‌ای (LDH) بر روی سطوح بیوچار و هیدروچار، به‌ترتیب ترکیب‌های LDH-بیوچار و LDH-هیدروچار ساخ...
The role of lactate dehydrogenase (LDH) in the generation of the metabolic signal for insulin secretion was studied after stable overexpression in INS-1 and RINm5F insulin-producing cells. INS-1 cells with a 25-fold overexpression of LDH-A, the highest level achieved, showed a 20-30% decrease in the glucose oxidation rate at glucose concentrations above 5 mM when compared with control cells, wh...
We recently notedthe presence of a sixth lactate dehydrogenase (EC 1.1.1.27) isoenzyme (LDH-6) in a previously well patient with chest and abdominal trauma. The patient, a 60year-old woman with hypertension but without other significant medical history, was involved in a motor vehicle accident with clavicular and rib fractures and a ruptured spleen. Her systolic pressure dropped into the 80’s (...
The presented work shows the synthesis and characterization of Zn/Ti layered double hydroxide (LDH) intercalated with carbonate dodecyl sulfate ions following its application as a functional filler in LDPE order to improve thermal properties resistance degradation UV-Vis radiation. X-ray diffractogram patterns LDH-CO3 LDH-DDS present basal spacing value 6.81 Å 38.09 Å, respectively, indicating ...
Although lactate dehydrogenase (LDH) serum levels, indirect markers of angiogenesis, are associated with a worse outcome in several tumours, their prognostic value is not defined in pancreatic cancer. Moreover, high levels are associated even with a lack of efficacy of tyrosine kinase inhibitors, contributing to explain negative results in clinical trials. We assessed the role of LDH in advance...
Lactate dehydrogenase (LDH) activities were measured in cerebrospinal fluid in 350 patients with various neurological diseases to establish the sensitivity and specificity of the CSF LDH as a marker for the diagnosis of leptomeningeal metastases. Slight elevations of CSF LDH were observed in nonmalignant diseases, while marked elevations were observed in a considerable number of patients with b...
Soluble lactate dehydrogenase (EC 1.1.1.27) extracted from brain, skeletal and cardiac muscle and liver of rats, and purified isoenzymes LDH-1 and LDH-5, were incubated with sodium deoxycholate. Deoxycholate almost totally inactivated isoenzyme LDH-5 (A4), whereas it left isoenzyme LDH-1 (B4) unaffected. Tissue lactate dehydrogenase was inactivated to different degrees depending on the origin o...
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