The crude extract of Sterculia tragacantha was subcutaneously infiltrated at the scrotum and left flank of West African dwarf goat prior to orchidectomy and non invasive flank procedures respectively. To assess the local anaesthetic efficacy of the extract post orchidectomy, the pain threshold, changes in vital parameters and blood glucose were monitored. Post flank infiltration, the durations ...

BACKGROUND AND AIMS Laryngoscopy and endotracheal intubation are associated with reflex sympathetic stimulation, known as pressor response and can cause major complications. We compared the attenuating effect of time-tested lignocaine versus clonidine on the hemodynamic response to laryngoscopy and intubation in neurosurgical cases. DESIGN A prospective, randomized, comparative, double-blind ...

OBJECTIVE To compare saline with and without added lignocaine and carbon dioxide distension for out patient hysteroscopy with regards to patient discomfort and hysteroscopic view. DESIGN Single blind prospective randomised controlled trial. SETTING Specialist out patient clinics in a large teaching hospital. POPULATION Women undergoing out patient hysteroscopy and endometrial biopsy for a...

BACKGROUND/AIMS To determine whether topical 2% lignocaine (lidocaine) gel is an effective anaesthetic agent for chalazion surgery. METHODS In a randomised controlled clinical trial, 57 subjects aged 12 years or over requiring incision and curettage for chalazion were recruited over an 8 month period. Patients were randomised into two groups. One group received 1.5 ml of lignocaine 2% injecti...

Many toxins from scorpion venoms activate sodium channels, thereby enhancing neurotransmitter release. The aim of the present work was to determine if the in vivo and in vitro effects of Leiurus quinquestriatus venom (LQQ) could be ameliorated by lignocaine, a sodium channel blocker. In urethane anaesthetised rabbits, LQQ venom (0.5 mg kg(-1), i.v.) caused initial hypotension and bradycardia fo...

PURPOSE To analyze whether preinstillation of lignocaine potentiates mydriasis by tropicamide in dark eyes and to determine possible mechanisms for this effect. METHODS This investigation was conducted in two phases, the first being a double-masked, placebo-controlled, randomized clinical trial, enrolling 60 healthy dark brown eyes in 30 subjects aged 7 to 58 years. The control eye received a...

eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. Acta Anaesthesiol Scand 1987;31: 735-9. 8 Hallen B, Olsson GL, Uppfeldt A. Pain-free venepuncture. Effect of timing of application of local anaesthetic cream. Anaesthesia 1984;39:%9-72. 9 Hopkins CS, Buckley CJ, Bush GH. Pain-free injection in infants. Use of a lignocaine-priloca...

Aims & Objectives: To evaluate the effect of Dexmedetomidine & Ketamine as an adjuvant to Lignocaine hydrochloride 0.5% 40ml in IVRA and to assess quality of anaesthesia, postoperative analgesia and side effects for hand or forearm surgery. Material & Method: Ninety patients were randomly assigned to three groups to receive IVRA for hand and forearm surgery: 40 ml of 0.5% Lignocaine and either ...

BACKGROUND This study evaluated the effectiveness of local lignocaine gel application in pain control during first-trimester suction termination of pregnancy (STOP). METHODS In this prospective randomized placebo-controlled double-blind trial, 131 women undergoing STOP between 7 and 10 weeks of gestation were studied. They were computer-randomized to receive 2% lignocaine gel or placebo (KY J...

BACKGROUND AND AIMS Ultrasonography has emerged as a novel, portable, non-invasive tool encouraging airway assessment and procedural interventions. This study assesses the feasibility of ultrasound for block of internal branch of superior laryngeal nerve (ibSLN) block during upper airway anaesthesia to aid awake fibre-optic intubation. METHODS Forty American Society of Anesthesiologists' phys...