Riyad T. Ellati, Parviz K. Kavoussi, Terry T. Turner, Jeffrey J. Lysiak From the Department of Urology, University of Virginia Health System, USA Purpose: This review addresses different aspects of testicular torsion from the clinical perspective as well as the basic cellular and molecular events responsible for the post-torsion testicular changes and pathology, including tissue ischemia-reperf...

NIKOLIC-HEITZLER, V., RABUZIN, F., TATZBER, F., VRKIC, N., BULJ, N., BOROVIC, S., WONISCH, W., SUNKO, B.M. and ZARKOVIC, N. Persistent Oxidative Stress after Myocardial Infarction Treated by Percutaneous Coronary Intervention. Tohoku J. Exp. Med., 2006, 210 (3), 247-255── Acute myocardial infarction causing cardiac ischemia is responsible for the majority of cardiac related deaths. Medical inte...

Signal transducer and activator of transcription (STAT) 3 is involved in mediating a broad range of biological processes, including cell survival, proliferation, and immune response. Recent evidence has indicated that STAT3 in cardiomyocytes can be activated by ischemic-oxidative stress and exerts cardioprotection in the ischemic heart. There is no information, however, regarding the effect of ...

With the advances in percutaneous coronary intervention technology and accompanying medical therapy, the prognosis of patients with acute coronary syndromes has greatly improved over the last decades. Still, approximately 6% of admitted patients do not survive to hospital discharge,1 and despite the implementation of rapid interventional protocols, loss of cardiac tissue, and a consecutive decr...

antifibrotic therapies should preferentially be targeted to the activated hepatic mesenchymal cells. those cells resemble wound healing myofibroblasts and synthesize an excess of extracellular matrix (ecm) proteins. they derive from quiescent hepatic stellate cells (hsc) and portal/perivascular (myo-) fibroblasts (mf). whereas various agents have been shown to inhibit hsc/mf proliferation and c...

background maintenance of the adequate intraoperative renal perfusion is very important during orthotopic liver transplantation (olt) to prevent acute renal failure. objectives for the first time, this study was designed to survey the effects of octreotide on urine output during anesthesia for olt and early postoperative renal function. patients and methods in this randomized double-blind place...

conclusions ferric chloride is an effective haemostatic agent in controlling liver parenchymal tissue hemorrhage in an animal model. results the hemostasis time of ferric chloride concentration groups was significantly less than that of the control group (p value < 0.001). the pathologic examination showed the highest frequency of low grade inflammation based on the defined pathological grading...