نتایج جستجو برای: mahasen val
تعداد نتایج: 7000 فیلتر نتایج به سال:
The tryptic peptides from human pepsin and gastricsin were purified and their sequences were determined. The sequence of 27 residues at the COOH-terminal end of human pepsin was found to be: -Ile-Leu-Gly-Asp-Val-Phe-Ile-ArgGln-Phe-Tyr-Thr-Val-Phe-Asp-Arg-Ala-Asn-Asn-GlnVal-Gly-Leu-Ala-Pro-Val-Ala. The sequence of 19 residues at the COOH-terminal end of human gastricsin was found to be: -Gln-Phe...
The following sequences of amino acids surrounding the three sulfhydryl groups of the Escherichia coli tryptophan synthetase A protein were established: Sequence I, Gly-IleAsp-Glu-Phe-Tyr-Ala-Gln-Cys-Glu-Lys-Val-Gly-ValAsp-Ser-Val-Leu-Val-Ala-Asp-Val-Gln-Glu-Ser-Ala-ProPhe-Arg; Sequence II, Arg-Ala-Phe-Ala-Ala-Gly-Val-ThrPro-Ala-Gln-Cys-Phe-Glu-Met-Leu-Ala-Leu-Ile-Arg; Sequence III, Arg-His-Asn...
Valyl-tRNA synthetase (ValRS) strictly discriminates the cognate L-valine from the larger L-isoleucine and the isosteric L-threonine by the tRNA-dependent "double sieve" mechanism. In this study, we determined the 2.9 A crystal structure of a complex of Thermus thermophilus ValRS, tRNA(Val), and an analog of the Val-adenylate intermediate. The analog is bound in a pocket, where Pro(41) allows a...
these tripeptides was studied by using monolayercultured human intestinaJ Caco-2 cells which express rnany enterocyte-Iike functions including the peptide transporter(PepTl)-mediated transport system. ValPro-Pro, an ACE-inhibitors peptide from fermented milk, was used as a model tripeptide. A significant amount of intact Val-Pro-Pro was transported across the Caco-2 cel) monolayer. This transpo...
Oriented and unoriented M13 coat protein, incorporated into dimyristoyl phosphatidylcholine bilayers, has been studied by (13)C-magic angle spinning nuclear magnetic resonance (MAS NMR) spectroscopy. Rotational resonance experiments provided two distance constraints between Calpha and C&z.dbnd6;O positions of the labelled residues Val-29/Val-30 (0.4+/-0.5nm) and Val-29/Val-31 (0.45+/-0. 5nm) in...
Background and purpose: Non-alcoholic fatty liver disease (NAFLD) is the major reason for abnormal liver function and is associated with obesity. Omentin (ITLN1) gene is highly expressed in visceral adipose tissue. The plasma omentin level is inversely correlated with obesity and serum omentin is elevated in patients with fatty liver diseases. This study investigated the association between Val...
Background and purpose: CYP1B1 is involved in the metabolism of exogenous and endogenous substrates and plays a key role in hormone and xenobiotic induced carcinogenesis. Polymorphisms in CYP1B1 could result in modifications in its enzyme activity and are known to be associated with cancer susceptibility related to environmental toxins and hormone exposure. Moreover, the association of CYP1B1 p...
The catechol-O-methyltranferase (COMT) is one of the main enzymes that metabolise dopamine in the brain. The Val158Met polymorphism in the COMT gene (rs4680) causes a trimodal distribution of high (Val/Val), intermediate (Val/Met) and low (Met/Met) enzyme activity. We tested whether the Val158Met polymorphism is a modifier of the age at onset (AAO) in Parkinson's disease (PD). The rs4680 was ge...
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