نتایج جستجو برای: mechanical properties of cortical bone

تعداد نتایج: 21248540  

Journal: :cell journal 0

objective: tendon never returns to its complete biological and mechanical properties after repair. bone marrow and, recently, adipose tissue have been used as sources of mesenchymal stem cells which have been proven to enhance tendon healing. in the present study, we compared the effects of allotransplantation of bone marrow derived mesenchymal stromal cells (bmscs) and adipose derived stromal ...

پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی استان کرمانشاه 1370

cml in breif cml is characterized by the proliferation of large numbers of immature wbc in the blood and bone marrow. in most of the patients , it is a clonal disorder in which all cell lines, express the philadelphia chromosome)q/22 translocation(it accounts for 20 of all leukemias and most cases occur over 25 yrs of age. the disease usually begins insidiously,but symptoms referable to anemia ...

2015
A. F. Pereira B. Javaheri A. A. Pitsillides S. J. Shefelbine

The development of predictive mathematical models can contribute to a deeper understanding of the specific stages of bone mechanobiology and the process by which bone adapts to mechanical forces. The objective of this work was to predict, with spatial accuracy, cortical bone adaptation to mechanical load, in order to better understand the mechanical cues that might be driving adaptation. The ax...

Journal: :International journal for numerical methods in biomedical engineering 2014
Abdelwahed Barkaoui Abdessalem Chamekh Tarek Merzouki Ridha Hambli Ali Mkaddem

The complexity and heterogeneity of bone tissue require a multiscale modeling to understand its mechanical behavior and its remodeling mechanisms. In this paper, a novel multiscale hierarchical approach including microfibril scale based on hybrid neural network (NN) computation and homogenization equations was developed to link nanoscopic and macroscopic scales to estimate the elastic propertie...

2013
Jun Wang Takuya Ishimoto Takayoshi Nakano

Mechanical loading plays a key role in altering macroscopic and microscopic bone structure through functional adaptation; however, the anisotropic micro-organization of collagen and biological apatite (BAp) in adaptively created bone tissue is not well understood in spite of its importance in the mechanical function of bone. In this study, we artificially applied axial compressive loading (15N ...

2011
Yumie Rhee Matthew R Allen Keith Condon Virginia Lezcano Ana C Ronda Carlo Galli Naomi Olivos Giovanni Passeri Charles A O'Brien Nicoletta Bivi Lilian I Plotkin Teresita Bellido

The periosteal and endocortical surfaces of cortical bone dictate the geometry and overall mechanical properties of bone. Yet the cellular and molecular mechanisms that regulate activity on these surfaces are far from being understood. Parathyroid hormone (PTH) has profound effects in cortical bone, stimulating periosteal expansion and at the same time accelerating intracortical bone remodeling...

2016
S Gohin A Carriero C Chenu AA Pitsillides TR Arnett M Marenzana

There is strong evidence that vasodilatory nitric oxide (NO) donors have anabolic effects on bone in humans. Parathyroid hormone (PTH), the only osteoanabolic drug currently approved, is also a vasodilator. We investigated whether the NO synthase inhibitor L-NAME might alter the effect of PTH on bone by blocking its vasodilatory effect. BALB/c mice received 28 daily injections of PTH[1-34] (80 ...

Journal: :Collegium antropologicum 2011
Natasa Draca Ana Tikvica Domagoj Eljuga Damir Semenski Mladen Brncić Slobodan Vukicević

Sevelamer hydrochloride is used for ten years in patients on dialysis as a phosphate binder. We have previously shown that oral application of sevelamer prevents the bone loss and increases the bone volume in ovariectomized rats. In this study we further analysed the biomechanical properties of bones from rats treated with sevelamer utilizing a threepoint bending test to determine the mechanica...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید