Introduction The integrated patient-centered, evidence-based approach to care recognizes the role of patient preferences. A discrete choice experiment (DCE) was developed with aim identifying preferences men prostate cancer in Italy regarding different risk-benefit factors various treatment options. Methods DCE support patients and oncologists based on a targeted scoping review. final included ...

Background: Urothelial carcinoma of the bladder is common cancer. Despite advances in treatments and introduction immune checkpoint inhibitors recent years, metastatic disease carries a poor prognosis

Breast cancer is a prevalent disease worldwide, and the majority of deaths occur due to metastatic disease. Clinical studies have identified a specific pattern for the metastatic spread of breast cancer, termed organ tropism; where preferential secondary sites include lymph node, bone, brain, lung, and liver. A rare subpopulation of tumor cells, the cancer stem cells (CSCs), has been hypothesiz...

Abstract: Aim/Background: Metastasis is the main reason of death in cancer with a key challenge to target it precisely by available treatments. The current study was designed assess anti-metastatic potentials synthesized chalcones, Ch-1 and Ch-2. Materials Methods: In vitro included cytotoxicity, scratch wound assay cell cycle analysis vivo performed C57BL/6 mice B16-F10 induced metastatic lung...

BACKGROUND The epidemiology of metastatic gastric cancer is unexplored because cancer registries seldom cover metastatic involvement apart from "present or not". We used a novel approach by utilizing Swedish registers to assess metastatic spread in gastric cancer. To our knowledge, this is the first nationwide description of metastases in gastric cancer. RESULTS The most common sites of metas...

By Nicolas Sayegh, Nishita Tripathi & 13 more. A study on survival outcomes in patients with metastatic castration-sensitive prostate cancer (mCSPC) undergoing intensified androgen deprivation therapy (ADT)

Engineered vaccinia virus-based therapy shows promising results in patients with advanced hepatocellular carcinoma, although a strategic virus design for the metastatic liver and the study of its efficacy in treating the cancer has not been well assessed. In this paper, we proposed a simple and strategic virus design for targeting metastatic hepatocellular carcinoma. We developed an evolutionar...

gastric cancer has been known as a poor prognosis disease with a high degree of mortality. in iran, it has been increased during the previous two decades, especially in northern part of the country. the aim of this study was to determine the demographic and clinical characteristics of gastric cancer in mazandaran province. all patients with gastric cancer diagnosis treated in the imam khomeini ...