Pseudomonas aeruginosa is a ubiquitous environmental bacterium and an opportunistic pathogen with the ability to rapidly develop multidrug resistance under selective pressure. Previous work demonstrated that upon exposure to the environmental contaminant pentachlorophenol (PCP), P. aeruginosa PAO1 increases expression of multiple multidrug efflux pumps, including the MexAB-OprM pump. The curren...

abstract        background and objectives: pseudomonas aeruginosa is the most frequent opportunistic pathogen isolated from the sputum of patients with cystic fibrosis (cf). resistance to β -lactam antibiotics may arise from over expression of the naturally occurring ampc cephalosporinases or acquired extended-spectrum β-lactamases (esbl). the aim of this study was to determine the antibiotic r...

one of the great challenges in the treatment of infectious diseases is the resistance of pathogenic bacteria against antibiotics, and antibiotic resistance to shigella is broadly observed in different parts of the world. the object of this study was to determine shigella antibiotic resistance pattern against the antibiotics such as ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, chloram...

background and objectives: the appearance of antibiotic resistance in streptococcus pneumoniae has raised a global concern over the past three decades. this study was conducted to determine the antimicrobial susceptibility of s. pneumoniae isolated from patients in children´s medical center (cmc) hospital during 2001 to 2011. materials and methods: during the 11 years period, a total of 194 s. ...

Background: The emergence and propagation of different phylogenetic groups of antimicrobial-resistant E. coli have become a worldwide health concern in human and veterinary medicine. Therefore, the evaluation of the phylogenetic distribution of antibiotic-resistant E. coli is important for therapeutic and economic purposes. The aims of this study were to determine phylogenetic groups and patter...

Introduction: Almost 80% of nosocomial urinary tract infections (UTIs) are due to catheterization. Catheter-associated UTI (CAUTI) is the primary source for colonization of antibiotic-resistant pathogens, and uropathogenic Escherichia coli (UPEC) is the most common causative bacteria. This study was conducted to determine the phylogenetic groups, and antibiotic resistance pattern as the two imp...

The present study aimed to evaluate the antibiotic resistance pattern of Escherichia coli strains isolatedfrom animals to ascertain the levels of antibiotic resistance pervasiveness. A total of 28 E. coli strains wereisolated from faecal samples and the antibiotic resistance pattern of E. coli strains was determined by meansof disc diffusion assay. The resistance pattern determined for all stra...

Background: Pseudomonas aeruginosa biofilm is one of the problems in antibiotic treatment of infections. Nanomedicines such as chitosan can carry multiple drugs and improve the therapeutic effects of antibiotics. Objectives: The study aimed to synthesis and characterization of ciprofloxacin loaded chitosan nanoparticle for eradication biofilm of P. aeroginosa. Methods: Cipro-CS microparticles...