in this research,qsar study has been carried out on quinolizidinyl derivatives as potent inhibitors of acetyl and butyrylcholin esterase in alzheimer’s disease. despite significant research efforts in both industry and academia, there are currently no diseases modifying therapies available to treat this illness. significant evidence suggests that the pathology of ad is linked to generation of β...

quantitative relationships between molecular structure and azolo-adamantanes derivatives were discovered by different chemometric tools including factor analysis based multiple linear regressions (fa-mlr), principle component regression analysis (pcra), and genetic algorithm-partial least squares ga-pls. the fa-mlr describes the effect of geometrical and quantum indices on enzyme inhibition act...

one of the most important aspects of software project management is the estimation of cost and time required for running information system. therefore, software managers try to carry estimation based on behavior, properties, and project restrictions. software cost estimation refers to the process of development requirement prediction of software system. various kinds of effort estimation patter...

BACKGROUND The present investigation compared parenting practices in a sample of preschoolers whose mothers reported smoking during pregnancy versus those who did not. METHODS A sample of n = 216, 3.0- to 5.11-year-old children, participants in an ongoing longitudinal study, was separated into those reportedly exposed to smoking in utero and those who were not. Parenting practices were compar...

In this work quantitative structure activity relationship (QSAR) methodology was applied for modeling and prediction of cellular response to polymers that have been designed for tissue engineering. After calculation and screening of molecular descriptors, linear and nonlinear models were developed by using multiple linear regressions (MLR) and artificial neural network (ANN) methods. The root m...

Ruminal bacteria and protozoa provide excellent organic phosphorus (P) sources for the host animal. This experiment was conducted to compare the bioavailability of bacterial and protozoal P in comparison with that of dicalcium phosphate (DCP) as a reference phosphorus source. Bacteria and protozoa were isolated from the rumen contents of dairy cows and the chick-model was used to determine the ...

One of the most important aspects of software project management is the estimation of cost and time required for running information system. Therefore, software managers try to carry estimation based on behavior, properties, and project restrictions. Software cost estimation refers to the process of development requirement prediction of software system. Various kinds of effort estimation patter...

This study was conducted to determine the location of DNA segment with homology to the rat conserved genomic DNA in human chromosomes. The labeled rat genomic DNA was hybridized with normal human (male) metaphases. The study of 74 metaphases after fluorescence in situ hybridization showed 371 twin-spot signals on human chromosomes. Statistical analysis indicated that the specific accumulation o...