Arise, awake, and stop not till the goal is reached e Katha Upanishad, chapter 1.3.14 Every journey starts with a small step forward, and every step in it carries a dream along. The initial steps in this journal's odyssey were by the founder editor, Prof: Johnson Francis, and he carried it as a dream formany years of this journey. Many joined him, nurtured the journal well and helped it grow up...

As one of the most intensively studied transcription factors, it is unsurprising that p53 is involved in many biological processes, including cell cycle arrest, DNA repair, senescence and apoptosis.1 its activities are mainly regulated by posttranslational modifications and interactions with other cellular components. Over the past few years, p53 has also been linked to redox homeostasis, the b...

In the 6th Century BCE the Chinese philosopher Laozi (Lao Tzu) wrote in the Daodejing (Tao Te Ching), “A journey of a thousand miles begins with a single step.” The first step of the journey upon which Pulmonary Circulation is now embarked was taken this past March, with the publication of Volume 1, Number 1, and the present issue is our second step. Where will this journey lead? Inevitably, as...

One of the major problems in modeling natural signals is that signals with very similar structure may locally have completely different measurements, e.g., images taken under different illumination conditions, or the speech signal captured in different environments. While there have been many successful attempts to address these problems in application-specific settings, we believe that underly...

Guaranteed Annuity Options (GAOs) are options available to holders of certain pension policies. Under these contracts, policyholders contribute premiums into a fund managed by the insurer. At retirement, the policyholders buy life annuities at a guaranteed rate provided by the original insurer, or annuitize with another insurer. If the guaranteed annuity rates are better than the prevailing rat...

This article assesses insurance uptake in three community-based health insurance (CBHI) schemes located in rural parts of two of India's poorest states and offered through women's self-help groups (SHGs). We examine what drives uptake, the degree of inclusive practices of the schemes and the influence of health status on enrolment. The most important finding is that a household's socio-economic...