We describe a patient with progressive hyperpigmentation of the skin and gas-trointestinal melanosis. The pigmented lesions in the stomach and duodenum served as a diagnostic sign of recurrent disease, 26 years after excision of melano-ma of the skin. A barium swallow and gastroduodenos-copy were performed in a healthy 63-year-old man who had been suffering from vague abdominal symptoms for a f...