objective: the aim of the present study was to estimate crude and age-standardized incidence rates for oral and pharyngeal nonsquamous cell malignant tumors in kerman province over a period of 11 years. materials and methods: the data used in this retrospective population-based study were extracted from the records registered in all pathology centers of kerman province from 1991 to 2001. all co...

Urethan was administered to newborn Syrian white hamsters to disclose their neoplastic competence. The first treatment was given within 24 hr of birth, and four subse quent injections were given at 3-day intervals. The survivors were sacrificed at 120 weeks of age. The urethan-treated animals developed malignant melano mas which metastasized to regional lymph nodes, lungs, kidneys, and liver. N...

tured human melanocytes in vitro and included two malignant melanomas in his report of a large series of tissue cultures. Subsequent studies on the growth of normal and neoplastic human melano cytes were carried out by Takano (18), Timofeyev ski (19), Sano and Smith (17), Grand and Cam eron (8), Fjelde (6), and Funan Hu (7). All these authors concluded that growth in tissue culture was characte...

objective: oral non- hodgkin’s lymphoma (nhl) is a relatively rare neoplasm that may develop in the soft tissues or jaw bones, with or without node or marrow involvement. oral lymphomas are often difficult to diagnose as there are no characteristic clinical features and usually appear as non-tender swellings.   case: we describe clinical, radiographic, histopathological and immunohistochemical ...

melanoma of the oral cavity is a rare malignant disease. on account of the presence at relatively obscure areas in the oral cavity, most of oral malignant melanomas are diagnosed at a late stage. early diagnosis is essential for successful treatment and perhaps is the key factor in improving the prognosis of oral malignant melanoma. however, no large clinical series exist, and in fact, clinical...

Ultraviolet (UV) irradiation is a risk factor for development of malignant melanoma. UVA-induced lysosomal exocytosis and subsequent cell growth enhancement was studied in malignant melanoma cell lines and human skin melanocytes. UVA irradiation caused plasma membrane damage that was rapidly repaired by calcium-dependent lysosomal exocytosis. Lysosomal content was released into the culture medi...

background: qat (also known as khat , kat and miraa ) is a green-leaved plant ( catha edulis ). it is a shrub indigenous to yemen and certain parts of eastern africa. chewing the leaves, which have sympathomimetic and euphoric effects, has been documented in many countries and increased with worldwide migration. the effect of long-term chewing qat on the oral cavity is unknown. objective: a sys...