Resveratrol, which is a polyphenolic antioxidant, is dose-dependent when used to provide health benefits, to enhance stress resistance, and to extend lifespans. However, even though resveratrol has therapeutic benefits, its clinical therapeutic effect is limited owing to its low oral bioavailability. An Escherichia coli system was developed that contains an artificial biosynthetic pathway that ...

Isoflavone glucosides are valuable nutraceutical compounds and are present in commercial fermentations, such as the erythromycin fermentation, as constituents of the soy flour in the growth medium. The purpose of this study was to develop a method for recovery of the isoflavone glucosides as value-added coproducts at the end of either Saccharopolyspora erythraea or Aeromicrobium erythreum ferme...

Cosmos caudatus Kunth. or “king’s salad” contains high values of nutritional compounds that act as health promoters. Although widely consumed for its medicinal value, information on phytochemical contents and their biosynthesis in the species is scarce. Among interesting are anthocyanins possess a dual role; an antioxidant natural colorant. A complete anthocyanin biosynthetic pathway C. was elu...

Diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. Due to the anti-diabetic and antioxidant activity of pelargonidin (PG), this research study was conducted to evaluate the efficacy of chronic oral PG on alleviating learning and memory disturbance in streptozotocin-diabetic rats. Male Wistar rats were divided into...

Cancer is a genetic disease in which cells are unable to control their functions normally. As cancer develops, old will survive when they should die, and new grow not needed. These extra can divide endlessly form growths called tumors . This research was carried out know whether peristrophine, apioside, pelargonidin 3-Sambubioside compounds could be developed as drug Non-Small Cell Lung (NSCLC)...

As the most significant secondary metabolites in plants with various beneficial properties, polyphenols have an increased demand for industrial use. These issues prompted exploratory studies on to be utilized as natural sources. Kitolod (Hippobroma longiflora (L.) G.Don ) has potential source because of abundant amount nature weed and is known a traditional herb based ethnobotanical studies. Th...

ECENT applications of chromatographic techniques ( BATE-SMITH 1948,1949) R have facilitated identification of anthocyanin pigments and related compounds in micro quantities, thus permitting extension of the combined genetic and biochemical work initiated by SCOTT-MONCRIEFF (1931) and extended by many others. The genetic studies by the late D. W. DAVIS and his associates (1958) on the inheritanc...

Six new germacranolides, zawadskinolides A-F (1-6), and a new eudesmane glucoside, chrysantiloboside (7) were isolated from the aerial parts of Dendranthema zawadskii var. latilobum, along with thirteen known constituents. Their structures were elucidated by means of spectroscopic evidence. Bioassay showed that flavonoids such as apigenin (9), (-)-eriodictyol (10) and nepetin (12), as well as t...

Diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. Due to the anti-diabetic and antioxidant activity of pelargonidin (PG), this research study was conducted to evaluate the efficacy of chronic oral PG on alleviating learning and memory disturbance in streptozotocin-diabetic rats. Male Wistar rats were divided into...

A new iridoid glucoside, 8-O-acetylshanzhiside (1), was isolated from the aerial parts of Phlomis tuberosa, together with two known iridoid glucosides, shanzhiside methyl ester and lamalbide. The known phenylethanoid glycosides acteoside and forsythoside B were also obtained and characterized. The structure of 1 was determined by means of 1D- and 2D-NMR spectroscopic evidence.