نتایج جستجو برای: penetration enhancers
تعداد نتایج: 41740 فیلتر نتایج به سال:
Transdermal patches are now widely used in topical and transdermal drug delivery systems (TDDS). Up to now, TDDS has been used in several conditions, such as smoking cessation, analgesic effect, nausea, contraception, and hormone therapy. Basically, there are two types of transdermal patches: the reservoir-type patches and the matrix-type patches. First generation TDDS were designed for deliver...
BACKGROUND/AIMS The skin has become very attractive as a route for drug administration. Optimization of topical drug formulations by the addition of penetration enhancers may facilitate the passage of drugs through the stratum corneum. METHODS In this paper, the skin penetration effect of phytosphingosine and 9 derived phytoceramides (PCERs) on 3 transdermal model drugs (i.e. caffeine, testos...
Diseases of the skin can cause harm and emotional distress in patients. The desirable drug is one with least complications and most effectiveness. By prolongation of target exposure, drug effectiveness could be improved. There are several suggested solutions, including the use of chemical enhancers, electroporation, iontophoresis, and the use of nanoparticles as carriers of pharmaceutical age...
Tissue optical clearing technique provides a prospective solution for the application of advanced optical methods in life sciences. This paper gives a review of recent developments in tissue optical clearing techniques. The physical, molecular and physiological mechanisms of tissue optical clearing are overviewed and discussed. Various methods for enhancing penetration of optical-clearing agent...
Invasomes are the liposomal vesicles embodying small amounts of ethanol and terpenes or terpene mixtures, which act as potential carriers with increased skin penetration. Invasomes have higher penetration rate through the skin as compared to liposomes and ethosomes. Invasomes provide a number of advantages including improving the drug’s efficacy, enhancing patient compliance and comfort. This a...
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