BACKGROUND In sarcoidosis, peripapillary subretinal neovascularization is rare. The role of corticosteroid therapy for subretinal neovascularization is controversial. CASE A 38-year-old female patient weighing 38 kg with histologically diagnosed sarcoidosis presented with peripapillary subretinal neovascularization, retinal phlebitis, a hyperemic disc, and snowball vitreous opacities in the l...

Aims. To compare optical coherence tomography angiography (OCT-A) retinal vasculature measurements between normal and optic atrophy after nonarteritic anterior ischemic optic neuropathy (NAION) subjects. Design. This prospective observational study was conducted between July 2015 and August 2016 at the ophthalmology outpatient department of a referral center in Taiwan. Peripapillary (4.5 × 4.5 ...

PURPOSE To measure the pulsatile movement of neuroretinal tissue at the optic nerve head synchronous with the cardiac cycle. METHODS We used a noninvasive imaging device based on Fourier domain low-coherence interferometry to measure the pulsatile movements of the optic nerve head, peripapillary retina, and cornea with submicron accuracy along a line across the fundus. We also measured the ch...

Assessment of the peripapillary nerve fiber layer and macular thickness can be determined in ophthalmology using optical coherence tomography (OCT). Decreased nerve fiber layer thickness and macular ganglion cell thickness in optic nerve ischemia have been correlated with visual field loss. OCT allows deep optic nerve head evaluation which helps understand pathophysiology of diseases.  Furtherm...

PURPOSE. To examine the biomechanical deformation of load bearing structures of the optic nerve head (ONH) resulting from raised intracranial pressure, using high definition optical coherence tomography (HD-OCT). The authors postulate that elevated intracranial pressure induces forces in the retrolaminar subarachnoid space that can deform ONH structures, particularly the peripapillary Bruch's m...

We thank Jonas and colleagues1 for their interest in our recent paper.2 We agree with the assertion from Jonas and colleagues1 that the biomechanics of the optic nerve dura mater, especially during eye movements, may have strong implications for various structural changes observed in highly myopic eyes. For instance, our models may be able to provide explanations about the optic disc rotation a...

Aim: To report the unusual SD-OCT findings in peripapillary subretinal space of blunt traumatic optic neuropathy (TON). Methods: All patients underwent a comprehensive eye examination included color fundus photography, ultrasonography, fluorescein angiography, visual field, PVEP if patient’s vision was allowed to examine. An orbital CT scan performed for all and no fracture found. However, we d...

AIMS To examine the effects of 0.5% apraclonidine on optic nerve head (ONH) and peripapillary retinal blood flow by scanning laser Doppler flowmetry (SLDF). METHODS ONH and peripapillary retinal blood flow of 17 healthy subjects were measured by SLDF before and 1 hour and 3 hours after unilateral administration of 0.5% apraclonidine. The fellow eyes were treated with balanced salt solution an...

PURPOSE To investigate the relationship between retinal nerve fiber layer (RNFL) thickness and retinal pigment epithelium alterations in patients with advanced glaucomatous visual field defects. METHODS A consecutive, prospective series of 82 study eyes with primary open-angle glaucoma and advanced glaucomatous visual field defects were included in this study. All study participants underwent...