From the Departments of Molecular Pharmacology and Experimental Therapeutics and Medicine, Mayo Medical School, Mayo Clinic, and Mayo Foundation, Rochester, Minn. Address reprint requests to Dr. Weinshilboum at the Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Medical School–Mayo Clinic– Mayo Foundation, Rochester, MN 55905, or at [email protected]. he pro...

Views on pharmacogenetics and gene therapy systematically differ across European countries. But despite a complex regulatory regime there is a balance of support, albeit laced with considerable uncertainty.

Approximately 50 years ago, pharmacogenetics emerged as a new field of medicine that may explain human drug action. Anesthesia, in particular, played a key role in these early investigations. An understanding of how an individual’s genetic footprint influences drug metabolism and effectiveness may allow tailored prescriptions, improving outcomes and safety; and such concepts, which form the bac...

In the last several years pharmacogenetics and pharmacogenomics have attracted the interest of the scientific community and of important pharmaceutical groups. What is the consequence for medicine and for the pharmaceutical industry? What has emerged from this investment, and what can we expect for the future? As with many new technologies, pharmacogenetics and pharmacogenomics were first adapt...