Both drug use and sex work considered as serious health and social problems. This study aimed to find the relation between them in young Iranian women. A mixed method of data collection applied from 300 young female sex workers in Tehran and 39 in-depth interviews with key informants. Result show that 84.4 % of participants used drugs before sex work. 46.2% of their fathers and 56.6% of their h...

Poly(acrylamide-co-acrylic acid) hydrogels, poly(AAm-co-AAc), were synthesized by free radical polymerization in solution using N,N’-methylenebisacrylamide (MBAAm) as the crosslinker. The structural parameters and the swelling behavior of the synthesized hydrogels were investigated for varying nominal crosslinking ratio and composition of the hydrogels. The use of hydrogels for drug release was...

Abstract Scientists are currently working to develop more effective and less harmful methods of delivering drugs tissue. One method is use a special type carrier help the drug get right place in body. In this study, an organometallic framework nanocarrier with formula IRMOF-3 [Zn 4 O(NH 2 -BDC) 3 ] was successfully prepared, containing magnetic nanoparticles manganese ferrite (MnFe O ) doxorubi...

The addition of 3'-deoxyadenosine (cordycepin) to cells in culture results in the inhibition of the appearance of mRNA in the cytoplasm through a mechanism thought to involve the inhibition of polyadenylate synthesis. I studied the effect of 3'-deoxyadenosine triphosphate, the physiologically active form of 3'-deoxyadenosine, on RNA release from isolated nuclei. Nuclei were isolated from baby-h...

giant unilamellar vesicles (guvs) consisting in self-closed lipid bilayers of 0.5-100 µm diameter are considered as oversimplified models of cells because of their biological membrane and micrometric size while large unilamellar vesicles (luvs) of 100-500 nm diameter have applications in drug delivery. to improve structural and mechanical properties of these vesicles, we have developed two cate...

As one kind of “smart” material, thermogelling polymers find applications in biofabrication, drug delivery and regenerative medicine. In this work, we report a thermosensitive poly(2-oxazoline)/poly(2-oxazine) based diblock copolymer comprising thermosensitive/moderately hydrophobic poly(2-N-propyl-2-oxazine) (pPrOzi) hydrophilic poly(2-ethyl-2-oxazoline) (pEtOx). Hydrogels were only formed whe...

Irrational drug use is associated with adverse consequences including drug resistance and avoidable adverse drug reactions. Studies of rational drug use in psychiatric facilities are scanty. This study evaluated prescription practices and perception of health care professionals regarding causes of irrational drug use. A retrospective study conducted at the outpatient clinic of Federal Neuropsyc...

We synthesized series of amphiphilic AB-type block copolymers having systematic variation in the core-forming segments using poly(lactide-co-depsipeptide)s as a hydrophobic segment and prepared polymeric micelles using the block copolymers, PEG-b-poly(lactide-co-depsipeptide). We then discussed the relationship between the core-forming segment structure and drug loading efficiency for the polym...