Barren, the Drosophila homolog of XCAP-H, is one of three non-SMC subunits of condensin, a conserved 13S multiprotein complex required for chromosome condensation. Mutations in barren (barr) were originally shown to affect sister-chromatid separation during mitosis 16 of the Drosophila embryo, whereas condensation defects were not detected. In contrast, mutations in yeast homologs of barren res...

A finite temperature many-particle theory of condensed matter systems is formulated using the functional Schrödinger picture. Using the interacting electron gas as a model system, we solve the equation of motion for the density matrix variationally with a Gaussian type trial density matrix. We show that the present formalism yields the finite temperature Hartree-Fock results both for the paraan...

We construct a Mach-Zehnder interferometer using Bose-Einstein condensed rubidium atoms and optical Bragg diffraction. In contrast to interferometers based on normal diffraction, where only a small percentage of the atoms contribute to the signal, our Bragg diffraction interferometer uses all the condensate atoms. The condensate coherence properties and high phase-space density result in an int...

The nucleus of round spermatids, the earliest haploid male germ cells, can participate in the formation of normal zygotes when incorporated into activated oocytes. In this study, we injected mouse round spermatids into homologous mature oocytes that were kept arrested at metaphase II to induce premature chromosome condensation (PCC) of the spermatid nuclei. After full condensation of the sperma...

The properties of systems with Bose-Einstein condensate in external time-independent random potentials are investigated in the frame of a self-consistent stochastic meanfield approximation. General considerations are presented, which are valid for finite temperatures, arbitrary strengths of the interaction potential, and for arbitrarily strong disorder potentials. The special case of a spatiall...

We compute the dynamical prefactor in the nucleation rate of bubbles or droplets in first order phase transitions for the case where both viscous damping and thermal dissipation are significant. This result, which generalizes previous work on nucleation, may be applied to study the growth of bubbles or droplets in condensed matter systems as well as in heavy ion collisions and in the expansion ...

To date, production of cloned rats by somatic cell nuclear transfer (NT) has not yet been successful. Inducing premature chromosome condensation (PCC) of injected cell nuclei in recipient cytoplasm is considered essential for successful mouse cloning by the Honolulu method. In the present study, some factors affecting PCC of rat cumulus cell nuclei injected into rat oocytes were examined. Wista...

The object of this study was to apply the phenomenon of premature chromosome condensation to the prediction of the future course of the disease in leukemic patients during chemotherapy and to the forecasting of relapse if they are in complete remission. The proliferative potential index (PPI) of bone marrows from leukemic patients was compared with that of solid tumor patients with no bone marr...