introduction: the molecular mechanisms involved in pathogenesis of esophageal cancer have been the main concern of several studies. in this study, we aimed to investigate the changes of serum prooxidant-antioxidant balance (pab) value as a redox index, as well as serum c-reactive protein (crp) compared to healthy control group. materials and methods: in a cross-sectional study, blood samples we...

Oxidative stress occurs as a result of imbalance between the antioxidant and prooxidant systems acting at certain points in metabolic processes, in favor of the last. The oxidative stress, defined by H Sies following extensive research performed between 1981 and 1993, is the outcome of intense generation of reactive oxygen species (ROS), which are not counteracted by endogenous antioxidant mole...

Antioxidants are the essential defense mechanism to protect the body against free radical damage. The objective of the study was to investigate the in vitro antioxidant activity of different parts of Withania somnifera (leaves, fresh tubers and dry tubers) towards free radical DPPH and the extent of inhibition of lipid peroxidation using hydrogen peroxide as prooxidant. The plant extracts exhib...

Background. Male infertility is one of the most serious medical and social problems. Idiopathic accounts for about 30 % cases infertile men. Rheumatoid arthritis associated with a decreased fertility potential. The aim present work was to determine lipid peroxidation level activity antioxidant enzymes such as glutathione peroxidase reductase in seminal plasma blood men idiopathic concomitant au...

Phenolic acids existed in many agricultural products especially vegetables and considered as important natural antioxidants. Eleven phenolic commonly were chosen to assess the antioxidant activities using DPPH·, ·ABTS+, ·O2-, ·OH scavenging assays, well ferric reducing power ?-carotene bleaching assays. The results showed that caffeic protocatechuic acid with simple dihydroxylation structures h...

Objective(s): We intended to determine whether the ovarian varicose which is one of the common etiologies of the pelvic congestion syndrome, has the ability to interfere with the DNA methylation reprogramming in the oocyte and thereby affect the oocyte quality or not. Materials and Methods: Varicose model was induced according to the Turner’s method in the rats. Briefly, a 20-gauge needle was p...

Independently, both inactivity and hypoxia augment oxidative stress. This study, part of the FemHab project, investigated the combined effects of bed rest-induced unloading and hypoxic exposure on oxidative stress and antioxidant status. Healthy, eumenorrheic women were randomly assigned to the following three 10-day experimental interventions: normoxic bed rest (NBR;n= 11; PiO2 = 133 mmHg), no...

Grapes are rich in polyphenolic compounds, which known for their beneficial effects on human health. Grape stems byproducts of the winemaking procedure. They exert antioxidant effects; however, they can also become pollutants when discarded without control into environment due to high organic content. The main aim present study was examine potential prooxidant/anticancer grape stem extracts, pr...