Erfan Daneshi

Department of Anatomy, Kurdistan University of Medical Sciences, Sanandaj, Iran

[ 1 ] - The effect of the ovarian varicose vein on the DNA methylation in the rat’s oocyte

Objective(s): We intended to determine whether the ovarian varicose which is one of the common etiologies of the pelvic congestion syndrome, has the ability to interfere with the DNA methylation reprogramming in the oocyte and thereby affect the oocyte quality or not. Materials and Methods: Varicose model was induced according to the Turner’s method in the rats. Briefly, a 20-gauge needle was p...

[ 2 ] - The effect of aminoguanidine on sperm motility and mitochondrial membrane potential in varicocelized rats

Objective(s): Increased levels of nitric oxide (NO) in the testicular veins of people suffering from varicocele have already been reported. However, the role of NO-synthase (NOS) isozymes and their inhibitors have not been extensively studied. We aimed to evaluate the inhibitory effects of aminoguanidine (AG), on sperm motility, vitality, and mitochondrial membrane potential (MMP) in varicoceli...

[ 3 ] - The effects of unilateral varicose ovarian vein on antioxidant capacity and oocyte quality in rat ovary

Objective(s): Several researchers have reported the relationship between infertility in male and varicocele for so many years but the implication of varicocele in female patients is remains elusive. Here, we aim to examine the effects of unilateral varicose ovarian vein on antioxidant capacity and oocyte quality of rat ovary after the experimental creation of varicocele in female rats. Material...

[ 4 ] - اثر تجویز تاموکسیفن در دوره بارداری بر ساختار بافتی لوله‌های منی‌ساز موش‌های نر بالغ

Introduction: Tamoxifen is a nonsteroidal drug which mainly treats breast cancer. It is also applied for stimulation of ovulation and remedy of infertility. Regarding the tamoxifen binding to estrogen receptors and the possible role of estrogens in spermatogenesis, the present study aimed to histologically evaluate spermatogenesis in the seminiferous ducts of mice, whose mothers had received ta...

[ 5 ] - Protective effect of Nigella sativa on sperm parameters in mice exposed to titanium dioxide during embryonic development

Background and Aim: Nanotechnology is the precise and controlled manipulation of the atomic or molecular structure of nanoscale materials for the preparation of particulate matter with new properties and specific applications. Many in vivo and in vitro studies have shown the negative and destructive effects of nanoparticles on male germ cells.Nanoparticles include primary particles with at leas...

[ 6 ] - The protective Effect of Nigella sativa on sperm parameter in mice treated with dexamethasone

Background and Aim: Dexamethasone affects testis hemostasis through reduction of  testosterone level . In one study dexamethasone induced spermatogenesis defects through epithelial vacuolizations and sloughing of germ cell layer. Material and Methods: Forty NMRI mice were randomly divided into four groups. Control and dexamethasone groups received normal saline and dexamethasone (5 mg/kg) respe...