ABSTRACT Prostate specific antigen (PSA) is a specific marker of prostate tumor which is used for diagnosis of prostate cancer. Apart from prostate cancer,different factors may affect PSA level and ejaculation is one of these possible factors .In a study on 21 patients at ages of 18-37, serum levels of PSA were measured before the ejaculation and about two hours after it. There was no statisti...

Abstract Background: Removal of prostate and radiotherapy are used routinely for treatment of prostate cancer however in advanced stages of the disease these treatments are ineffective. Researchers are exploring strategies for preventing this malignancy. This study aims to design and develop a phage based vaccine for preventing prostate cancer. Materials and methods: After conducting bioinforma...

Abstract Background: Since hydro-alcohol concentration of Thymus Vulgaris plays a role in prevention of any growth disorders and separation of cells and cancer, therefore this research intends to study the effect of mentioned concentration and DMBA (a type of chemical cancer factor) on the weight and histo-pathologic properties of prostate of the desert mouse–Wistar race. Materials and meth...

Background: MiRNAs are one of the most important genetic regulators that regulate more than 50 percent of the human genome. MiR-124-a-3 is a tumor suppressor miRNA which its expression dramatically reduced in prostate cancer tumor cells. Since miRNA binding to the transcript of target genes by seed sequence, any mutations and changes in this region could be effective on its performance and iden...

  Background and Aim: Prostate cancer is one of the most prevalent type of cancer and the second cause of death among American men. Its prevalence has a direct relationship with increasing age. The present study was carried out to determine the level of prostate specific antigen (PSA) in Birjandi males aged between 40 and 80 years.   Material and Methods: In this prospective study, out of 62...

 Background: In recent years the use of Prostate Specific Antigen test (PSA) has reduced the mortality rate of prostate cancer. Certain factors by affecting the levels of PSA, decrease or increase prostate cancer detection. Some studies suggest the effect of body weight and Body Mass Index (BMI) on PSA, while some others are contrary to the opinion mentioned.. Hence, in this study we ex...