نتایج جستجو برای: protein antigens
تعداد نتایج: 1319136 فیلتر نتایج به سال:
Brucellosis is caused by the bacterium Brucella and affects various domestic and wild species. GroEL (Heat Shock Protein 60kDa) as one of the major antigens that stimulate the immune system, increases Brucella survival. The aim of the current study was to clone and express GroEL in Escherichia coli in order to design subunit vaccine. Amplifying was performed using specific primers. The full-len...
Brucellosis, caused by Brucella spp., is an important zoonotic disease that causes abortion and infertility in cattle and undulant fever in humans. Various studies have examined cell-free native and recombinant proteins as candidate protective antigens in animal models. Among Brucella immunogenes, antigen based on ribosomal preparation has been widely investigated. In this study, the immunogeni...
In vitro lymphocyte responses of high responder (HR) and low responder (LR) guinea pigs from pe-ripheral blood lymphocytes (PBL) to parasite antigens soluble protein third stage larvae (SPL3) and soluble protein adult stage ( SPA), non-parasite antigen ovalbumin (OVA) were examined. There was substantial differences between HR and LR guinea pigs in the rate of acquisition of responsiveness to t...
The E3 19,000-dalton protein termed "E3/19K" of adenovirus type 2 binds to human class I histocompatibility antigens (HLA antigens). Human 293.12 cultured cells that express a cloned gene for the E3/19K protein show reduced levels of HLA antigens on the cell surface compared to parental 293 cells. We have transfected these cell lines with plasmid DNA containing the murine histocompatibility H-2...
Abstract The development of a universal influenza vaccine to protect against variants will be the priority goal in combating virus infection. In this study, we exploited novel type protein nanoparticles consisting NP as core and NA1-M2e or NA2-M2e fusion proteins coating antigens by using an SDAD heterobifunctional crosslinker. Intramuscular immunization NP/NA-M2e (core/shell) induced increased...
سرطان عامل اصلی مرگ در کشورهای توسعه یافته اقتصادی و دومین عامل مرگ در کشورهای در حال توسعه است. سرطان کولورکتال یکی از سومین سرطان رایج و چهارمین دلیل مرگ و میر در جهان است. سرطان کولورکتال در ایران، در مردان، چهارمین سرطان بوده و در زنان دومین سرطان محسوب می¬شود. بیشترین مرگ و میر ناشی از سرطان کولورکتال به علت متاستاز دادن آن است. تشخیص زود هنگام و اتخاذ روش های درمانی مناسب برای این افراد ا...
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