Pyrethroid insecticides are widely used for pest control in agriculture or in human public health commonly as a topical treatment for scabies and head lice. Exposure to pyrethroids such as permethrin or tetramethrin (TM) causes sensory alterations such as transient pain, burning, stinging sensations, and paraesthesias. Despite the well-known effects of pyrethroids on sodium channels, actions on...

Deltamethrin and piperonyl butoxide two synthetic pyrethroids, when used in a combination it produces synergistic effect. This insecticide has found to be widely the management of mosquito, housefly other insects control various vector born diseases. In this review we assessed toxic effect deltamethrin on beneficial organisms commonly available ecosystem. It was fish, honey bees prime pollinato...

Na channels are the primary molecular targets of the pyrethroid insecticides. Na channels consisting of only a type IIA a subunit expressed in Chinese hamster ovary cells responded to pyrethroid treatment in a normal manner: a sustained Na current was induced progressively after each depolarizing pulse in a train of stimuli, and this Na current decayed slowly on repolarization. These modified N...

Synthetic pyrethroids such as cypermethrin, deltamethrin and permethrin, which are usually used in pest control operations, are metabolized to 3-phenoxybenzoic acid (3-PBA) and excreted in urine. Though 3-PBA can be used to assess exposure to pyrethroids, there are few reports describing urinary 3-PBA levels in Japan. This study aimed to investigate the seasonal variation of the exposure levels...

Pyrethroids are widely-used chemical insecticides, to which humans are commonly exposed, and known to alter functional expression of drug metabolizing enzymes. Limited data have additionally suggested that drug transporters, that constitute key-actors of the drug detoxification system, may also be targeted by pyrethroids. The present study was therefore designed to analyze the potential regulat...

Background: Pyrethroids are generally of low toxicity to humans, but in suicidal poisonings which are usually associated with ingestion of high doses, they lead to severe systemic effects. Case Report: A 30-year old woman presented to emergency department with a history of intentional ingestion of about 15 mL of prallethrin around 3 days earlier. She complained of shortness of breath along with...

Exposure to pesticides is very common world-wide, and is broadly known the acute toxic effects to humans of pesticides following a high dose exposure; however, knowledge about chronic low-dose adverse effects to specific pesticides is more limited. Reproductive functions can be affected, with birth defects, impaired fecund ability, infertility and altered growth. This paper will focus on the de...

background: malaria is the most important vector-borne disease in many tropical countries all over the world. because of the widespread use of pyrethroid insecticide treated mosquito nets in the world, the effects of excito-repellency (er) phenomenon of pyrethroids against main malaria vector, anopheles stephensi were studied. methods: the er phenomenon of three concentrations of two synthetic ...

Insecticide susceptibility in tobacco budworm, Heliothis virescens (F.) (Lepidoptera: Noctuidae), was determined for 8 yr (1991-2001) with larvae sampled from cotton in southern Tamaulipas, Mexico. Before 1996, when Bollgard cotton expressing the Cry1A(c) delta-endotoxin was introduced into the region, two important patterns were documented. The first was economically significant increases in r...

The threat of environmental pollution, biological warfare agent dissemination and new diseases in recent decades has increased research into cell-based biosensors. The creation of this class of sensors could specifically aid the detection of toxic chemicals and their effects in the environment, such as pyrethroid pesticides. Pyrethroids are synthetic pesticides that have been used increasingly ...