Using a Tecan robotic sample processor and IBM compatible PCs we have developed a flexible, partially automated radioligand binding assay system. It handles pipetting parameters of up to 16 saturation or competition experiments at a time with up to 24 radioligand- or competitor-concentrations in a range over 4 orders of magnitude per experiment. The system provides enough flexibility so that al...

In this research, we investigate how well Weibull, Gamma, and special bimodal distribution are suited as an alternative to the exponential distribution approach in the stochastic modeling of machine downtimes and times between failures. We also discuss the question whether sampling shop-floor data should not only include first order statistics, but also measures that allow to monitor and model ...

A significant fraction of data stored in cloud storage is rarely accessed. This data is referred to as cold data; cost-effective storage for cold data has become a challenge for cloud providers. Pelican is a rack-scale harddisk based storage unit designed as the basic building block for exabyte scale storage for cold data. In Pelican, server, power, cooling and interconnect bandwidth resources ...

Housing systems for laboratory animals have been developed over a long time. Micro-environmental systems such as positive, individually ventilated caging systems and forced-air-ventilated systems are increasingly used by many researchers to reduce cross contamination between cages. There have been many investigations of the impact of these systems on the health of animals, the light intensity, ...

A multi-state latching translation stage is demonstrated using microelectromechanical systems technology. The mechanism is fabricated in bonded silicon-on-insulator material with an 85 μm thick bonded layer, by single-layer patterning, deep reactive ion etching, undercutting and metallization. The table position can be continuously adjusted by electrothermal buckling mode actuators or latched i...

This article explores the development of previous models to determine hubs in a competitive environment. In this paper, by comparing parameters of the ticket price, travel time and the service quality of hub airports, airline hubs are divided into six categories. The degree of importance of travel time and travel cost are determined by a multivariate Lagrange interpolation method, which can pla...

The paper presents a modelling framework for activity scheduling process. The modelling framework considers Random utility maximization (RUM) assumption for its components in order to dynamically capture the joint activity type, location and continuous time expenditure choice tradeoffs over the course of the day. The dynamics of activity scheduling process are modeled by considering the history...

BACKGROUND/AIMS Attention-deficit/hyperactivity disorder (ADHD) is often overlooked in adults; moreover, the problem seems to be even more critical in women. In the present, observational screening study, a clinical, particularly adult outpatient population was examined regarding frequency and severity of a likely ADHD, whereby sex differences were of particular interest. METHODS 224 particip...