نتایج جستجو برای: ras models
تعداد نتایج: 935979 فیلتر نتایج به سال:
Hyperactivated Ras regulates many oncogenic pathways in several malignant human cancers including glioblastoma and it is an attractive target for cancer therapies. Ras activation in cancer cells drives protein internalization via macropinocytosis as a key nutrient-gaining process. By utilizing this unique endocytosis pathway, here we create a biologically inspired nanostructure that can induce ...
The aim of this study was to investigate the role of specific cytotoxic T lymphocytes (CTLs) activated by dendritic cells (DCs) presenting cationic nanoparticles with the K-ras (12-Val) mutant peptide in the killing of different pancreatic cancer cell lines in vivo and in vitro. Peripheral blood DCs were induced by rhGM-CSF and IL-4 and cultured. DCs were sensitized by whole antigen of PANC-1 w...
The development of cancer reflects the complex interactions and properties of many proteins functioning as part of large biochemical networks within the cancer cell. Although traditional experimental models have provided us with wonderful insights on the behavior of individual proteins within a cancer cell, they have been deficient in simultaneously keeping track of many proteins and their inte...
colorectal cancer (crc) is one of the most common cancers worldwide. understanding of the tumor behavior, in a much closer look, at the molecular level, results in a more effective treatment and accurate prognosis of the disease. from among various genes altered in colorectal cancer k-ras is assumed to be of diagnostic and prognostic significance. k-ras mutations are believed to be a critical e...
Background: Recurrent aphthous stomatitis (RAS) is the most common inflammatory ulcerative condition of oral cavity. The aim of this study was to compare the levels of the salivary Malondialdehyde (MDA) and total antioxidant capacity (TAC) and blood parameter in RAS versus healthy controls. Methods: This case-control study consisted of 28 patients with RAS and 28 age and sex -matched control...
A physico-chemical model for the accumulation of sulfur species in raindrops is developed in which account is taken of the mass transfer of SO1, 0,, NH, and CO1 into ideal raindrops containing the catalyst Fe(II1). The sulfur accumulation was calculated for the droplets as a function of fall distance. The model predicts the formation of sulfate due to the oxidation of dissolved SO2 by 0, and ca...
Background: Recurrent aphthous stomatitis (RAS) is a common disease, which several etiologic factors have been considered for it. The infectious agents and immunological factors are the most suspected causes. Recently a few studies with varied results have been done to clarify the role of Helicobacter Pylori (H.pylori) in etiology of RAS. Objective: To find correlations between serum IgG and Ig...
Background and Aim: Recurrent aphthous stomatitis (RAS) is the most common oral mucosal lesion in the general population. Different treatments have been used for RAS, including herbal medicine. In this study, the randomized clinical trials (RCTs) on the effect of medicinal plants on RAS were systematically searched and reviewed. Materials and Methods: The literature from 1985 to 2015 in the ...
background and aims: recurrent aphthous stomatitis (ras) is one of the most common ulcerative diseases of the oral mucosa. definitive etiology of ras has not been conclusively established. there is no certain treatment for aphthous but some drugs such as steroid are commonly used for treatment of ras. regarding the effect of zinc on healing process of epithelial layer and cell division, in this...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید