The rpoA gene, encoding the alpha subunit of RNA polymerase, was cloned from Streptomyces coelicolor A3(2). It is preceded by rpsK and followed by rplQ, encoding ribosomal proteins S11 and L17, respectively, similar to the gene order in Bacillus subtilis. The rpoA gene specifies a protein of 339 amino acids with deduced molecular mass of 36,510 Da, exhibiting 64.3 and 70.7% similarity over its ...

We investigated the participation of prostaglandin (PG) E2 in the regulation of the alpha 1(I) procollagen gene expression by tumor necrosis factor alpha (TNF alpha), and interleukin-1 beta (IL-1 beta) in normal adult human lung fibroblasts. TNF alpha (100 units/ml) and IL-1 beta (100 units/ml) stimulated the production of PGE2 and caused a dose-dependent inhibition of up to 54 and 66%, respect...

Background:Brucella spp. are facultative intracellular pathogens that can cause chronic infections in many tissues and organs. Objectives: To investigate serum dermcidin, salusin-alpha, salusin-beta and TNF-alpha levels and their correlation with each other in patients with acute brucellosis. Methods: From 50 patients hospitalized upon...

In this article, we first give a modified Schwarz–Pompeiu formula in general sector ring with angle \(\vartheta =\frac{\pi }{\alpha },\ \alpha \ge 1/2\) by proper conformal mappings, and obtain the solution of Schwarz problem for Cauchy–Riemann equation explicit forms. Furthermore, construct some integral operators discuss their properties detail. Finally, virtue these operators, problems an in...

The human lymphocyte function-associated antigen-1 (LFA-1), the complement receptor-associated OKM1 molecule, and a previously undescribed molecule termed p150,95, have been found to be structurally and antigenically related. Each antigen contains an alpha- and beta-subunit noncovalently associated in an alpha 1 beta 1-structure as shown by cross-linking experiments. LFA-1, OKM1, and p150,95 al...

The independence number α ( G ) $\alpha (G)$ and the dissociation diss $\text{diss}(G)$ of a graph $G$ are largest orders induced subgraphs maximum degree at most 0 1, respectively. We consider possible improvements obvious inequality 2 ≥ $2\alpha (G)\ge \text{diss}(G)$ . For connected cubic graphs distinct from K 4 ${K}_{4}$ , we show 5 3 $5\alpha 3\,\text{diss}(G)$ describe rich interesting s...

We evaluated whether tolerance to the antagonism of bicuculine-induced seizures by diazepam is associated with changes (i) in the content of mRNAs encoding for gamma-aminobutyric acidA (GABAA) receptor subunits, (ii) in the expression density of these subunits, and (iii) in the 1,4-benzodiazepine binding site characteristics in discrete neocortical structures. We found that in diazepam-tolerant...

Tumor necrosis factor-alpha (TNF-alpha) has been associated with cachexia and is known to regulate multiple inflammatory cell (neutrophil and macrophage) responses. We tested the hypothesis that neutrophils and macrophages accumulate in the extensor digitorum longus (EDL) and soleus muscles of mice after chronic TNF-alpha administration. Murine recombinant TNF-alpha (approximately 100 microg x ...

The aims of this research was to investigate effect alpha-tocopherol on spermatozoa death in form apoptosis and necrosis rats (Rattus norvegicus) exposed 2,3,7,8- tetrachlorodibenzo-p-dioxin. Male were administered TCDD experimental groups. Five groups a combination alpha- tocopherol designed as follows; 0.5 ml corn oil (control negative group, K-), 700 ng/kg/d (treatment control), 77 (Group P1...