The potential role of airway interleukin-5 (IL-5) expression in eliciting mucus production was demonstrated in a pulmonary IL-5 transgenic mouse model (NJ.1726) in which naive transgenic mice display comparable levels of airway mucus relative to allergen-sensitized and -challenged wild-type mice. The intrinsic mucus accumulation of NJ.1726 was abolished in compound transgenic-gene knockout mice...

in this work, we investigate the transfer of some homological properties from a ring $r$ to its amalgamated duplication along some ideal $i$ of $r$ $rbowtie i$, and then generate new and original families of rings with these properties.

for a ring endomorphism $alpha$ and an $alpha$-derivation $delta$, we introduce a concept, so called skew $pi$-armendariz ring, that is a generalization of both $pi$-armendariz rings, and $(alpha,delta)$-compatible skew armendariz rings. we first observe the basic properties of skew $pi$-armendariz rings, and extend the class of skew $pi$-armendariz rings through various ring extensions. we nex...

in this paper, we introduce the new notion of n-f-clean rings as a generalization of f-clean rings. next, we investigate some properties of such rings. we prove that mn(r) is n-f-clean for any n-f-clean ring r. we also, get a condition under which the denitions of n-cleanness and n-f-cleanness are equivalent.

a topoframe, denoted by $l_{ tau}$,  is a pair $(l, tau)$ consisting of a frame $l$ and a subframe $ tau $ all of whose elements are complementary elements in$l$. in this paper, we define and study the notions of a$tau $-real-continuous function on a frame $l$ and the set of realcontinuous functions $mathcal{r}l_tau $ as an $f$-ring.we show that $mathcal{r}l_{ tau}$is actually a generalization ...

for a fixed positive integer , we say a ring with identity is n-generalized right principally quasi-baer, if for any principal right ideal of , the right annihilator of is generated by an idempotent. this class of rings includes the right principally quasi-baer rings and hence all prime rings. a certain n-generalized principally quasi-baer subring of the matrix ring are studied, and connections...

It is well established that the pre-T cell receptor for antigen (TCR) is responsible for efficient expansion and differentiation of thymocytes with productive TCRbeta rearrangements. However, Ptcra- as well as Tcra-targeting experiments have suggested that the early expression of Tcra in CD4- CD8- cells can partially rescue the development of alphabeta CD4+ CD8+ cells in Ptcra-deficient mice. I...

Dendritic cells (DCs) initiate and control immune responses. Plasmacytoid DCs (pDCs) represent a unique DC subset able to promptly release large amounts of type I interferon (IFN-alphabeta) upon viral encounter. Here we report that depletion of pDCs from human blood mononuclear cells abrogates the secretion of specific and polyclonal IgGs in response to influenza virus. Furthermore, purified pD...