Fifty-three psychiatric patients, 16 with schizophrenia, 19 with affective disorder, and 19 with schizo-affective disorder were diagnosed by Research Diagnostic Criteria. Hoffmann reflex recovery curves were measured in the right and left legs of each patient. In both affective disorder and schizo-affective disorder, recovery curve height in the right and left legs was highly correlated. In sch...

ôbjective: recently, quality of life is a concern of health in psychiatry. schizophrenia is a disorder that has the most regressive effects in societies’ and patients’ behavioural, occupational and psychiatric aspects. the main purpose of this study was to evaluate the quality of life and global function of schizophrenia patients. methods: â hundred schizophrenia patients (with dsm-ïv-tr) who h...

CONTEXT Cannabis-induced psychosis is considered a distinct clinical entity in the existing psychiatric diagnostic systems. However, the validity of the diagnosis is uncertain. OBJECTIVES To establish rate ratios of developing cannabis-induced psychosis associated with predisposition to psychosis and other psychiatric disorders in a first-degree relative and to compare them with the correspon...

OBJECTIVE There is renewed debate on whether modern diagnostic classification should adopt a dichotomous or dimensional approach to schizophrenia and bipolar disorder. This study synthesizes data from voxel-based studies of schizophrenia and bipolar disorder to estimate the extent to which these conditions have a common neuroanatomical phenotype. METHODS A post-hoc meta-analytic estimation of...

Objective: This is a case report discussing the comorbidity of obsessive compulsive disorder (OCD) and schizophrenia. Such clinical phenomenon merits recognition as a distinct subgroup of schizophrenia with unique challenges and treatment needs. Method: A case report presenting schizophrenia with preceding obsessive-compulsive disorder over five years. Results: This report describes the clinica...

Acute intermittent porphyria (AIP) has been associated with schizophrenia in some studies, but prior research is limited by the absence of comparison populations. Here, we linked Swedish registers to examine the risk of schizophrenia and bipolar disorder in 717 individuals diagnosed with AIP and their first-degree relatives, compared with matched individuals without AIP and their first-degree r...

Large-scale genetic association studies have identified replicable susceptibility alleles for some psychiatric phenotypes. 1 This includes both common and rare variants. A striking finding has been that susceptibility variants identified to date often confer susceptibility to more than one of the traditional clinical phenotypes , a finding that has the potential to increase understanding of the...

Schizophrenia and bipolar disorder, although diagnostically separate, likely share elements of their genetic etiology. This study assessed whether the COMT Val158Met polymorphism has shared or specific associations with clinical phenotypes evident in schizophrenia and bipolar disorder. Schizophrenia and bipolar patients completed a clinical assessment encompassing premorbid functioning and curr...

Background : personalized approach considering the effectiveness and safety of medication is main goal contemporary psychopharmacotherapy. Knowing special characteristics any given drug allows a practitioner to choose tactic meeting needs particular patient. The aim this narrative review was summarize data about use Brexpiprazole in pharmacotherapy different mental disorders. Method using keywo...