BACKGROUND The introduction of a central venous catheter in haemodialysis patients is an unpleasant procedure for the patient. Intravenous sedation is accepted practice in complicated endoscopic procedures but not often used in haemodialysis patients. METHODS We developed a protocol for the use of stepwise sedation in these patients with the use of midazolam and fentanyl. RESULTS Stepwise s...

INTRODUCTION AND OBJECTIVES The outcomes of atrial fibrillation ablation procedures vary widely between different centers. Our objective was to analyze the results and complications of this procedure in our center and identify factors predicting the efficacy and safety of atrial fibrillation ablation. METHODS In total, 726 atrial fibrillation ablation procedures were performed in our center b...

Providing effective analgesia and adequate sedation is a generally accepted goal of intensive care medicine. Due to its rapid, organ independent and predictable metabolism the short acting opioid remifentanil might be particularly useful for analgesia-based sedation in the intensive care unit (ICU). This hypothesis was tested by two studies in this issue of Critical Care. The study by Breen et ...

BACKGROUND AND OBJECTIVE to compare the therapeutic effects of ketamine alone or ketamine plus propofol on analgesia, sedation, recovery time, side effects in premedicated children with midazolam-ketamine-atropin who are prepared circumcision operation. METHODS 60 American Society of Anaesthesiologists physical status I-II children, aged between 3 and 9 years, undergoing circumcision operatio...

BackgroundCare bundles have demonstrated improved survival and functional recovery in patients with cardiac arrest who achieve return of spontaneous circulation (ROSC). Canadian literature has supported a post-ROSC bundle that includes targeted temperature management (TTM), coronary angiography, routine critical care management. TTM targets shifted, given new evidence suggesting equipoise betwe...

Abstract Funding Acknowledgements Type of funding sources: None. Background Atrial Fibrillation (AF) ablation has been performed successfully under different methods anesthesia and varies between centers, from general anaesthesia (GA) to conscious sedation. Recently, a novel pulsed-field (PFA, Farapulse) technology based on non-thermal become available for clinical use. To date, no structured s...

OBJECTIVE OF THE STUDY to analyze the efficiency and safety of Dexmedetomidine infusion for a short-term controlled sedation and treatment of delirium in the early postoperative period in patients after cardiac surgery. METHODS open, randomized, prospective study of 28 patients undergoing surgery on the heart or main blood vessels under general anaesthesia. In the early postoperative period a...

OBJECTIVE Deep sedation and delirium are common in the ICU. Mechanically ventilated patients with acute lung injury are at especially high risk for deep sedation, delirium, and associated long-term physical and neuropsychiatric impairments. We undertook an ICU-wide structured quality improvement project to decrease sedation and delirium. DESIGN Prospective quality improvement project in compa...

BACKGROUND This descriptive study provides the first information on an association between the use of sedation and a reduction in the prevalence of unsuccessful lumbar puncture (LP) in African children of all races. OBJECTIVE Our hypothesis was that children who do not receive any procedural sedation are more likely to have unsuccessful LPs. METHODS A cross-sectional observational study exa...

STUDY OBJECTIVES Three of the most commonly used agents for conscious sedation in the Emergency Department (ED) are ketamine, fentanyl/versed, and propofol. In this study, we measured and compared the total times spent in the ED with each of these agents. Our objective was to determine whether the use of propofol for conscious sedation was associated with a shorter length of ED stay as compared...