background: providing high-quality care in the intensive care units (icus) is a major goal of every medical system. nurses play a crucial role in achieving this goal. one of the most important responsibilities of nurses is sedation and pain control of patients. the present study tried to assess the effect of nurses’ practice of a sedation protocol on sedation and consciousness levels and the do...

OBJECTIVE To compare a practice of protocol-directed sedation during mechanical ventilation implemented by nurses with traditional non-protocol-directed sedation administration. DESIGN Randomized, controlled clinical trial. SETTING Medical intensive care unit (19 beds) in an urban teaching hospital. PATIENTS Patients requiring mechanical ventilation (n = 321). INTERVENTIONS Patients wer...

BACKGROUND We aimed to compare the effects of nursing-implemented sedation protocol and daily interruption of sedative infusion on the duration of mechanical ventilation. METHODS Fifty patients receiving mechanical ventilation and requiring sedation in the intensive care unit (ICU) were randomly selected to receive either daily interruption of sedative infusion (Group P, n=25) or nursing-impl...

STUDY OBJECTIVE To compare empiric and protocol-based therapies of sedation and analgesia in terms of pharmacologic cost, effects on mechanical ventilation and intensive care unit (ICU) stay, and quality of sedation and analgesia. DESIGN Prospective study. SETTING A 24-bed medical-surgical-neurologic ICU. PATIENTS Seventy-two patients evaluated during empiric therapy and 86 during protoco...

Background Identifying risk factors for unplanned extubation in patients receiving mechanical ventilation can help guide prevention strategies. Objective To assess the risk of unplanned extubation with different sedation strategies. Methods A 36-month quality improvement study in a 33-bed intensive care unit at a tertiary-care center. Results A total of 92 unplanned extubations occurred (7.5 ev...

BACKGROUND Identifying risk factors for unplanned extubation in patients receiving mechanical ventilation can help guide prevention strategies. OBJECTIVE To assess the risk of unplanned extubation with different sedation strategies. METHODS A 36-month quality improvement study in a 33-bed intensive care unit at a tertiary-care center. RESULTS A total of 92 unplanned extubations occurred (...

BACKGROUND Ventilator-associated pneumonia (VAP) is a common side effect in patients who receive intravenous sedation infusion. In routine care, after starting sedation infusion for patients who receive mechanical ventilation, interruption of sedation starts without protocol. This study aimed to evaluate the effect of daily sedation vacation protocol on the incidence of VAP in mechanically vent...

BACKGROUND Acute behavioural disturbance (ABD) is an increasing problem in emergency departments. This study aimed to determine the impact of a structured intramuscular (IM) sedation protocol on the duration of ABD in the emergency department. METHODS A historical control study was undertaken comparing 58 patients who required physical restraint and parenteral sedation with the structured IM ...

BACKGROUND Moderate to deep sedation has been recommended during endoscopic submucosal dissection (ESD). However, it is often accompanied by adverse events such as respiratory depression or aspiration pneumonia. This study investigated the respiratory complications and ESD outcomes of two sedation protocols: moderate sedation with analgesic supplementation (MSAS) and analgesia targeted light se...

OBJECTIVES To report the effectiveness and efficiency of a predetermined sedation protocol for providing sedation for electroencephalograph (EEG) studies in children with autism. METHODS Sleep EEG has been advocated for the majority of children with autism spectrum disorder. In most cases, sedation is required to allow adequate studies. Most sedation drugs have negative effects on the EEG pat...